Relationship between weight-adjusted-waist index and all-cause and cardiovascular mortality in individuals with type 2 diabetes

被引：5

作者：

Zhang, Tian-Yu ^{[1
]}

Zhang, Zi-Meng ^{[2
]}

Wang, Xue-Ning ^{[1
]}

Kuang, Hong-Yu ^{[1
]}

Xu, Qian ^{[1
]}

Li, Hong-Xue ^{[1
]}

Xu, Cheng-Ye ^{[1
]}

Zhao, Kang-Qi ^{[1
]}

Zhang, Cong ^{[1
]}

Hao, Ming ^{[1
]}

机构：

[1] Harbin Med Univ, Affiliated Hosp 1, Dept Endocrinol, 23 You Zheng St, Harbin 150001, Peoples R China

[2] Harbin Med Univ, Affiliated Hosp 1, Dept Ophthalmol, Harbin, Peoples R China

来源：

DIABETES OBESITY & METABOLISM | 2024年 / 26卷 / 12期

关键词：

mortality; NHANES; type; 2; diabetes; UK Biobank; weight-adjusted waist; OBESITY; ASSOCIATIONS; ADIPOSITY; ADULTS; RISK; FAT;

D O I：

10.1111/dom.15929

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aim: To investigate the relationship between the weight-adjusted-waist index (WWI) and all-cause mortality as well as cardiovascular mortality in individuals with type 2 diabetes. Methods: We used data from the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2018 and the UK Biobank database. Restricted cubic spline curves and Cox proportional hazards models were employed to assess hazard ratios (HRs) and 95% confidence intervals (CIs) for all-cause mortality. Results: In the UK Biobank database, compared with the lowest WWI quartile, the HR for all-cause and cardiovascular death in the highest quartile was 1.846 (95% CI 1.687-2.019) and 2.118 (95% CI 1.783-2.517), respectively, in the fully adjusted model. In the NHANES database, compared with the lowest WWI quartile, the highest quartile had an HR of 1.727 (95% CI 1.378-2.163) for all-cause death and 1.719 (95% CI 1.139-2.595) for cardiovascular death in the fully adjusted model. Conclusions: Our study indicates that WWI has a long-term synergistic negative impact on all-cause mortality and cardiovascular mortality in individuals with type 2 diabetes. The WWI is an independent predictor of mortality in individuals with type 2 diabetes.

引用

页码：5621 / 5629

页数：9