Suicide among patients with oral cancer: A population-based study

被引:11
作者
Wang, Guang-Rui [1 ]
Wang, Han-Qi [1 ]
Zhong, Nian-Nian [1 ]
Cao, Lei-Ming [1 ]
Li, Zi-Zhan [1 ]
Liu, Xuan-Hao [1 ]
Xiao, Yao [1 ]
Liu, Bing [1 ,2 ]
Bu, Lin-Lin [1 ,2 ]
机构
[1] Wuhan Univ, Sch & Hosp Stomatol, State Key Lab Oral & Maxillofacial Reconstruct & R, Key Lab Oral Biomed,Minist Educ,Hubei Key Lab Stom, Wuhan 430079, Peoples R China
[2] Wuhan Univ, Sch & Hosp Stomatol, Dept Oral & Maxillofacial Head Neck Oncol, Wuhan 430079, Peoples R China
关键词
Oral cancer; Suicide rate; Standardized mortality ratio; SEER database; Risk factors; ONCOLOGIST ALLIANCE; CAVITY CANCER; YOUNG-ADULTS; NECK-CANCER; RISK; HEAD; DIAGNOSIS; EPIDEMIOLOGY; SURGERY; LIFE;
D O I
10.1016/j.canep.2024.102625
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background: Patients with oral cancer usually experience disfigurement and dysfunction which are shared risk factors of suicide. The aim of the study was to comprehensively assess the characteristics of suicide and risk factors for suicide in patients with oral cancer. Methods: Surveillance, Epidemiology, and End Results database was used to acquire information of patients with common malignant tumors including oral cancer from 1975 to 2020. The aim was to explore the incidence of suicide, and timing of suicide among patients with oral cancer. A Fine-Gray competing risks regression model was employed to analyze risk factors associated with suicide among patients with various demographic and tumor characteristics. Results: Totally, 7685 patients with different malignant tumors committed suicide. Among them, 203 patients with oral cancer died due to suicide, presenting a suicide rate of 54.5/100,000 person-years, which was almost 3.5 times that of the US general population and 1.5 times that of the overall US patients with cancer in our study. Approximately 18 %, 40 %, and 55 % of suicides occurred in first year, first 3 years, and first 5 years after diagnosis. Being male, White race, and having a single primary tumor might be regarded as the risk factors for suicide. Conclusion: As oral cavity is closely associated with appearance, pronunciation and ingestion, patients with oral cancer have a significant high risk of suicide. Tremendous attention needs to be paid to patients with oral cancer particularly those exhibiting characteristics associated with a high risk of suicide.
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页数:8
相关论文
共 43 条
[1]   Demographic and clinical factors associated with suicide in gastric cancer in the United States [J].
Bowden, Mallory B. ;
Walsh, Nathaniel J. ;
Jones, Andrew J. ;
Talukder, Asif M. ;
Lawson, Andrew G. ;
Kruse, Edward J. .
JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2017, 8 (05) :897-901
[2]   Less is more: Exploring neoadjuvant immunotherapy as a de-escalation strategy in head and neck squamous cell carcinoma treatment [J].
Cao, Lei-Ming ;
Zhong, Nian-Nian ;
Chen, Yang ;
Li, Zi-Zhan ;
Wang, Guang-Rui ;
Xiao, Yao ;
Liu, Xuan-Hao ;
Jia, Jun ;
Liu, Bing ;
Bu, Lin-Lin .
CANCER LETTERS, 2024, 598
[3]   Lymph node metastasis in oral squamous cell carcinoma: Where we are and where we are going [J].
Cao, Lei-Ming ;
Zhong, Nian-Nian ;
Li, Zi-Zhan ;
Huo, Fang-Yi ;
Xiao, Yao ;
Liu, Bing ;
Bu, Lin-Lin .
CLINICAL AND TRANSLATIONAL DISCOVERY, 2023, 3 (04)
[4]  
Celik N, 2002, PLAST RECONSTR SURG, V109, P2211, DOI 10.1097/00006534-200206000-00005
[5]   Trends in clinical features and survival of oral cavity cancer: fifty years of experience with 3,362 consecutive cases from a single institution [J].
Chen, Shu-Wei ;
Zhang, Quan ;
Guo, Zhu-Ming ;
Chen, Wen-Kuan ;
Liu, Wei-Wei ;
Chen, Yan-Feng ;
Li, Qiu-Li ;
Liu, Xue-Kui ;
Li, Hao ;
Ou-Yang, Dian ;
Chen, Wei-Chao ;
Fu, Xiao-Yan ;
Wang, Xi-Di ;
Yang, An-Kui ;
Bei, Jin-Xin ;
Song, Ming .
CANCER MANAGEMENT AND RESEARCH, 2018, 10 :4523-4535
[6]   Surgical margins in head and neck squamous cell carcinoma: A narrative review [J].
Chen, Yang ;
Zhong, Nian-Nian ;
Cao, Lei-Ming ;
Liu, Bing ;
Bu, Lin-Lin .
INTERNATIONAL JOURNAL OF SURGERY, 2024, 110 (06) :3680-3700
[7]   Nasopharyngeal carcinoma [J].
Chen, Yu-Pei ;
Chan, Anthony T. C. ;
Quynh-Thu Le ;
Blanchard, Pierre ;
Sun, Ying ;
Ma, Jun .
LANCET, 2019, 394 (10192) :64-80
[8]   Suicide risk after cancer diagnosis among older adults: A nationwide retrospective cohort study [J].
Choi, Jae Woo ;
Park, Eun-Cheol .
JOURNAL OF GERIATRIC ONCOLOGY, 2020, 11 (05) :814-819
[9]   Head and Neck Cancer [J].
Chow, Laura Q. M. .
NEW ENGLAND JOURNAL OF MEDICINE, 2020, 382 (01) :60-72
[10]  
de Melo GM, 2001, ARCH OTOLARYNGOL, V127, P828