Harnessing Biopolymer Gels for Theranostic Applications: Imaging Agent Integration and Real-Time Monitoring of Drug Delivery

被引:3
|
作者
Jirvankar, Pranita [1 ]
Agrawal, Surendra [1 ]
Chambhare, Nikhita [1 ]
Agrawal, Rishabh [2 ]
机构
[1] Datta Meghe Inst Higher Educ & Res, Datta Meghe Coll Pharm, Wardha 442001, Maharashtra, India
[2] Bajiraoji Karanjekar Coll Pharm, Sakoli 441802, Maharashtra, India
关键词
biopolymer gel; real-time monitoring; imaging agent; NANOPARTICLES; THERAPY;
D O I
10.3390/gels10080535
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Biopolymer gels have gained tremendous potential for therapeutic applications due to their biocompatibility, biodegradability, and ability to adsorb and bind biological fluids, making them attractive for drug delivery and therapy. In this study, the versatility of biopolymer gels is explored in theranostic backgrounds, with a focus on integrating imaging features and facilitating real-time monitoring of drug delivery. Different methods of delivery are explored for incorporating imaging agents into biopolymer gels, including encapsulation, surface functionalization, nanoparticle encapsulation, and layer-by-layer assembly techniques. These methods exhibit the integration of agents and real-time monitoring drug delivery. We summarize the synthesis methods, general properties, and functional mechanisms of biopolymer gels, demonstrating their broad applications as multimodal systems for imaging-based therapeutics. These techniques not only enable multiple imaging but also provide signal enhancement and facilitate imaging targets, increasing the diagnostic accuracy and therapeutic efficacy. In addition, current techniques for incorporating imaging agents into biopolymer gels are discussed, as well as their role in precise drug delivery and monitoring.
引用
收藏
页数:15
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