Selecting multimodal therapy for rhabdomyosarcoma

被引：7

作者：

Sultan, Iyad ^{[2
]}

Ferrari, Andrea ^{[1
]}

机构：

[1] Fdn IRCCS Ist Nazl Tumori, Pediat Oncol Unit, I-20133 Milan, Italy

[2] King Hussein Canc Ctr, Dept Pediat Oncol, Irbid, Jordan

来源：

EXPERT REVIEW OF ANTICANCER THERAPY | 2010年 / 10卷 / 08期

关键词：

chemotherapy; multidisciplinary; pediatric; prognosis; radiotherapy; rhabdomyosarcoma; soft-tissue sarcoma; stratification; surgery; SOFT-TISSUE SARCOMA; PHASE-II WINDOW; INTENSITY-MODULATED RADIOTHERAPY; HIGH-DOSE CHEMOTHERAPY; STEM-CELL RESCUE; REFRACTORY SOLID TUMORS; INITIAL TESTING STAGE-1; UP-FRONT WINDOW; INTERGROUP-RHABDOMYOSARCOMA; METASTATIC RHABDOMYOSARCOMA;

D O I：

10.1586/ERA.10.96

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Rhabdomyosarcoma is a typical tumor of childhood, characterized by a high grade of malignancy, local invasiveness and a marked propensity to metastasize, but also a generally good response to chemotherapy and radiotherapy. Multimodal therapy is essential to cure rhabdomyosarcoma patients, but different uses of surgery, radiotherapy and chemotherapy, and their intensity, need to be selected and modulated to different patient risk groups. This article attempts to give an account of the current treatment options, the open and debated issues and the potential novel strategies for the near future.

引用

页码：1285 / 1301

页数：17

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