Impact of physical activity, physical fitness and exercises on cognitive impairment in patients with multiple sclerosis: A review of evidence and underlying mechanisms

被引:1
作者
Lenne, B. [1 ,2 ]
Donze, C. [1 ,2 ]
Massot, C. [1 ,2 ,3 ,4 ]
Degraeve, B. [1 ]
机构
[1] Lille Catholic Univ, Lille, France
[2] Grp Hop Inst Catholique Lille GHICL, Neurol Dept, Lille, France
[3] Univ Polytech Hauts De France UPHF, LAMIH, Valenciennes, France
[4] CNRS, UMR 8201, Valenciennes, France
关键词
Multiple sclerosis; Cognitive impairment; Cognitive rehabilitation; Physical activity; Physical exercise; QUALITY-OF-LIFE; RANDOMIZED CONTROLLED-TRIAL; INFORMATION-PROCESSING SPEED; TREADMILL WALKING EXERCISE; CARDIORESPIRATORY FITNESS; AEROBIC FITNESS; INHIBITORY CONTROL; TRAINING-PROGRAM; ASSOCIATION; HEALTH;
D O I
10.1016/j.neurol.2023.06.003
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Cognitive impairment in persons with MS (pwMS) occurs commonly, early and independently of other clinical features of the disease. MS-related cognitive impairment is mainly characterized by weakening of information processing speed, working memory and episodic memory. Much evidence, based on both neuropsychological and neuroimaging outcomes, highlights successful cognitive rehabilitation interventions. In this context, promotion of physical activity and exercise training could be a dual, motor and cognitive, rehabilitation method. The aim of this article is, firstly, to review existing evidence regarding the effects of exercise on cognition among pwMS, and secondly, to explore the possible mechanisms of action of the cognitive-motor coupling.
引用
收藏
页码:583 / 598
页数:16
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