In the Clinic Gastroesophageal Reflux Disease

被引:4
作者
Dunbar, Kerry B. [1 ,2 ]
机构
[1] VA North Texas Healthcare Syst, Dallas, TX 75216 USA
[2] Univ Texas Southwestern Med Ctr Dallas, Dallas, TX 75390 USA
关键词
PROTON-PUMP INHIBITORS; RANDOMIZED-TRIAL; ESOPHAGEAL PH; SYMPTOMS; METAANALYSIS; RISK; ACID; ASSOCIATION; MANAGEMENT; HEARTBURN;
D O I
10.7326/AITC202408200
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Gastroesophageal reflux disease (GERD) is a condition that occurs when reflux of gastric contents into the esophagus causes symptoms and/or complications. The prevalence of GERD in Western societies has been estimated at 30%, making it one of the most commonly encountered disorders in primary care. The spectrum of GERD includes typical symptoms of esophageal reflux (heartburn and/or regurgitation); esophageal injury (erosive esophagitis; stricture; Barrett esophagus; and, rarely, adenocarcinoma); and extraesophageal symptoms, such as hoarseness and chronic cough. Proper diagnosis and treatment of GERD includes symptom control, exclusion of other disorders, avoiding overuse of medications and invasive testing, and minimizing complications.
引用
收藏
页码:ITC113 / ITC128
页数:16
相关论文
共 77 条
[1]   Do proton pump inhibitors increase the risk of dementia? A systematic review, meta-analysis and bias analysis [J].
Ahn, Nayeon ;
Nolde, Michael ;
Krause, Evamaria ;
Guentner, Florian ;
Guenter, Alexander ;
Tauscher, Martin ;
Gerlach, Roman ;
Meisinger, Christa ;
Linseisen, Jakob ;
Baumeister, Sebastian-Edgar ;
Rueckert-Eheberg, Ina-Maria .
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2023, 89 (02) :602-616
[2]   Limited Ability of the Proton-Pump Inhibitor Test to Identify Patients With Gastroesophageal Reflux Disease [J].
Bytzer, Peter ;
Jones, Roger ;
Vakil, Nimish ;
Junghard, Ola ;
Lind, Tore ;
Wernersson, Borje ;
Dent, John .
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2012, 10 (12) :1360-1366
[3]   Updated meta-analysis of controlled observational studies: proton-pump inhibitors and risk of Clostridium difficile infection [J].
Cao, F. ;
Chen, C. X. ;
Wang, M. ;
Liao, H. R. ;
Wang, M. X. ;
Hua, S. Z. ;
Huang, B. ;
Xiong, Y. ;
Zhang, J. Y. ;
Xu, Y. L. .
JOURNAL OF HOSPITAL INFECTION, 2018, 98 (01) :4-13
[4]  
Carroll Thomas L, 2017, Laryngoscope, V127 Suppl 6, pS1, DOI [10.1002/lary.26806, 10.1002/lary.26806]
[5]   AGA Clinical Practice Update on the Diagnosis and Management of Extraesophageal Gastroesophageal Reflux Disease: Expert Review [J].
Chen, Joan W. ;
Vela, Marcelo F. ;
Peterson, Kathryn A. ;
Carlson, Dustin A. .
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2023, 21 (06) :1414-+
[6]   How many cases of laryngopharyngeal reflux suspected by laryngoscopy are gastroesophageal reflux disease-related? [J].
de Bortoli, Nicola ;
Nacci, Andrea ;
Savarino, Edoardo ;
Martinucci, Irene ;
Bellini, Massimo ;
Fattori, Bruno ;
Ceccarelli, Linda ;
Costa, Francesco ;
Mumolo, Maria Gloria ;
Ricchiuti, Angelo ;
Savarino, Vincenzo ;
Berrettini, Stefano ;
Marchi, Santino .
WORLD JOURNAL OF GASTROENTEROLOGY, 2012, 18 (32) :4363-4370
[7]   PPIs Are Not Responsible for Elevating Cardiovascular Risk in Patients on Clopidogrel-A Systematic Review and Meta-Analysis [J].
Demcsak, Alexandra ;
Lantos, Tamas ;
Balint, Emese Reka ;
Hartmann, Petra ;
Vincze, Aron ;
Bajor, Judit ;
Czopf, Laszlo ;
Alizadeh, Hussain ;
Gyongyi, Zoltan ;
Marta, Katalin ;
Miko, Alexandra ;
Szakacs, Zsolt ;
Pecsi, Daniel ;
Hegyi, Peter ;
Szabo, Imre Laszlo .
FRONTIERS IN PHYSIOLOGY, 2018, 9
[8]   Accuracy of the diagnosis of GORD by questionnaire, physicians and a trial of proton pump inhibitor treatment: the Diamond Study [J].
Dent, John ;
Vakil, Nimish ;
Jones, Roger ;
Bytzer, Peter ;
Schoning, Uwe ;
Halling, Katarina ;
Junghard, Ola ;
Lind, Tore .
GUT, 2010, 59 (06) :714-721
[9]   Heartburn, Nausea, and Vomiting During Pregnancy [J].
Dunbar, Kerry ;
Yadlapati, Rena ;
Konda, Vani .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2022, 117 (10S) :10-15
[10]   Association of Acute Gastroesophageal Reflux Disease With Esophageal Histologic Changes [J].
Dunbar, Kerry B. ;
Agoston, Agoston T. ;
Odze, Robert D. ;
Huo, Xiaofang ;
Pham, Thai H. ;
Cipher, Daisha J. ;
Castell, Donald O. ;
Genta, Robert M. ;
Souza, Rhonda F. ;
Spechler, Stuart J. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2016, 315 (19) :2104-2112