Plasmonic Nanogap Probes for Surface-Enhanced Raman Scattering-Based Bioimaging and Analysis

被引：3

作者：

Shin, Hyeon-Jeong ^{[1
]}

Yoo, Juyeon ^{[1
]}

Park, Eunhye ^{[1
]}

Song, Eun Ho ^{[1
]}

Nam, Jwa-Min ^{[1
]}

机构：

[1] Seoul Natl Univ, Dept Chem, Seoul 08826, South Korea

来源：

JOURNAL OF PHYSICAL CHEMISTRY C | 2024年 / 128卷 / 42期

基金：

新加坡国家研究基金会;

关键词：

SINGLE-MOLECULE; BIOMEDICAL APPLICATIONS; QUANTITATIVE DETECTION; GOLD NANOPARTICLES; FANO RESONANCES; LIVING CELLS; SERS; NANOSTRUCTURES; SPECTROSCOPY; PARTICLES;

D O I：

10.1021/acs.jpcc.4c04765

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Surface-enhanced Raman scattering (SERS) utilizes nanostructures to amplify Raman signals, making it a powerful tool for molecular detection and analysis. When plasmonic nanostructures are in close proximity, electromagnetic fields become highly localized in specific regions called hot spots. These regions, typically found in the gaps inside and between metal nanoparticles, significantly enhanced Raman signal intensity, enabling the detailed detection of biomolecules within cells. This review explores recent developments in the design and application of plasmonic nanogap structures for SERS, with a particular emphasis on their innovative applications in biological imaging. It highlights how these advances provide high-resolution, highly sensitive detection capabilities, potentially transforming bioimaging technologies.

引用

页码：17815 / 17824

页数：10

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