Architecture of the Mass Spectrometry Data Management Pipeline in the SMART-CARE Project

被引：0

作者：

Ringwald, Friedemann G. ^{[1
]}

Dudchenkoa, Aleksei ^{[1
,2
]}

Knaup, Petra ^{[1
]}

Czernilofsky, Felix ^{[2
]}

Dietrich, Sascha ^{[2
,3
]}

Ganzinger, Matthias ^{[1
]}

机构：

[1] Heidelberg Univ Hosp, Inst Med Informat, Heidelberg, Germany

[2] Heidelberg Univ, Dept Med 5, Hematol Oncol & Rheumatol, Heidelberg, Germany

[3] Univ Hosp Dusseldorf, Dept Hematol & Oncol, Dusseldorf, Germany

来源：

MEDINFO 2023 - THE FUTURE IS ACCESSIBLE | 2024年 / 310卷

关键词：

Systems medicine; mass spectrometry; data management;

D O I：

10.3233/SHTI231118

中图分类号：

TP18 [人工智能理论];

学科分类号：

081104 ; 0812 ; 0835 ; 1405 ;

摘要：

In the SMART-CARE project- a systems medicine approach to stratification of cancer recurrence in Heidelberg, Germany - a streamlined mass-spectrometry (MS) workflow for identification of cancer relapse was developed. This project has multiple partners from clinics, laboratories and computational teams. For optimal collaboration, consistent documentation and centralized storage, the linked data repository was designed. Clinical, laboratory and computational group members interact with this platform and store meta- and raw-data. The specific architectural choices, such as pseudonymization service, uploading process and other technical specifications as well as lessons learned are presented in this work. Altogether, relevant information in order to provide other research groups with a head-start for tackling MS data management in the context of systems medicine research projects is described.

引用

页码：1016 / 1020

页数：5

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