Acylglycine Analysis by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS)

被引：1
作者：
Hobert, Judith A. [1 ,2 ,3 ]
Guymon, Rebecca [2 ]
Yuzyuk, Tatiana [1 ,2 ,3 ]
Pasquali, Marzia [1 ,2 ,3 ]
机构：
[1] Univ Utah, Sch Med, Dept Pathol, Salt Lake City, UT 84132 USA
[2] ARUP Labs, Salt Lake City, UT 84108 USA
[3] Univ Utah, ARUP Inst Clin & Expt Pathol, Salt Lake City, UT 84132 USA
来源：
CURRENT PROTOCOLS | 2023年 / 3卷 / 04期
关键词：
acylglycine; fatty acid beta-oxidation; glycine N-acylase; organic acidemia; UPLC-MS/MS; URINARY ACYLGLYCINES; DIAGNOSIS; ISOVALERYLGLYCINE; QUANTIFICATION; DISORDERS; DEFECTS;
D O I：
10.1002/cpz1.758
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Quantitative analysis of urine acylglycines has shown to be a highly sensitive and specific method with proven clinical utility for the diagnosis of several inherited metabolic disorders including: medium chain acyl-CoA dehydrogenase deficiency, multiple acyl-CoA dehydrogenase deficiency, short chain acyl-CoA dehydrogenase deficiency, 3-methylcrotonyl-CoA carboxylase deficiency, 2-methylbutyryl-CoA dehydrogenase deficiency, isovaleric acidemia, propionic academia, and isobutyryl-CoA dehydrogenase deficiency. Here, a method that is currently performed using ultra-performance liquid chromatography/tandem mass spectrometry (UPLC-MS/MS) is described. (c) 2023 Wiley Periodicals LLC.
引用
收藏
页数：12
相关论文
共 50 条
[31]   Drug Screening of Whole Blood by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry [J].
Oiestad, Elisabeth Leere ;
Johansen, Unni ;
Oiestad, Ase Marit Leere ;
Christophersen, Asbjorg Solberg .
JOURNAL OF ANALYTICAL TOXICOLOGY, 2011, 35 (05) :280-293
[32]   Qualitative and quantitative analysis of ephedrine stimulants in urine by ultra-performance liquid chromatography-tandem mass spectrometry [J].
Zhu, Ting ;
Jin, Yao ;
Zhao, Jingjing ;
Jing, Jing ;
Tian, Tian ;
Shan, Yuanhong ;
Xu, Xin ;
Wang, Yang .
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2022, 36 (04)
[33]   Rapid Determination of Organonitrogen, Organophosphorus and Carbamate Pesticides in Tea by Ultrahigh-Performance Liquid Chromatography–Tandem Mass Spectrometry (UPLC-MS/MS) [J].
Hong-Xia Zhao ;
Shan-Cang Zhao ;
Li-Gang Deng ;
Jiang-Sheng Mao ;
Chang-Ying Guo ;
Guo-Sheng Yang ;
Xiao Lu ;
Hassan Y. Aboul-Enein .
Food Analytical Methods, 2013, 6 :497-505
[34]   Pharmacokinetic studies of novel berberine derivatives with ultra-performance liquid chromatography-tandem mass spectrometry [J].
Wang, Wenchao ;
Shen, Qin ;
Liang, Hui ;
Hua, Changlong ;
Liu, Yuhui ;
Li, Fengzhi ;
Li, Qingyong .
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 1031 :172-180
[35]   Measurement of ganciclovir concentration in human plasma by ultra-performance liquid chromatography-tandem mass spectrometry [J].
Rigo-Bonnin, Rauel ;
Padulles, Ariadna ;
Corral-Comesana, Sofia ;
Cerezo, Gema ;
Maria Grinyo, Josep ;
Colom, Helena ;
Alia-Ramos, Pedro ;
Lloberas, Nuria .
CLINICA CHIMICA ACTA, 2014, 427 :58-64
[36]   Determination and Pharmacokinetics of Delsoline in Rat Plasma by Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry [J].
Cai, Yuan ;
Zhou, Caiping ;
Chen, Yuyan ;
Liang, Qishun ;
Hu, Manman ;
Chen, Lianguo .
LATIN AMERICAN JOURNAL OF PHARMACY, 2021, 40 (03) :633-636
[37]   Determination of phenylephrine in human plasma using ultra-performance liquid chromatography-tandem mass spectrometry [J].
Feng, Sheng ;
Zhao, Qian ;
Jiang, Ji ;
Hu, Pei .
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2013, 915 :28-32
[38]   Quantitative analysis of multiple fatty acid ethanolamides using ultra-performance liquid chromatography-tandem mass spectrometry [J].
Lin, Lin ;
Yang, Haifeng ;
Jones, Peter J. H. .
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 2012, 87 (06) :189-195
[39]   A highly sensitive ultra performance liquid chromatography-tandem mass spectrometric (UPLC-MS/MS) technique for quantitation of protein free and bound efavirenz (EFV) in human seminal and blood plasma [J].
Avery, Lindsay B. ;
Parsons, Teresa L. ;
Meyers, David J. ;
Hubbard, Walter C. .
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2010, 878 (31) :3217-3224
[40]   Measurement of total and free docetaxel concentration in human plasma by ultra-performance liquid chromatography-tandem mass spectrometry [J].
Rigo-Bonnin, Raul ;
Cobo-Sacristan, Sara ;
Gonzalo-Diego, Nuria ;
Colom, Helena ;
Munoz-Sanchez, Carmen ;
Urruticoechea, Ander ;
Falo, Catalina ;
Alia, Pedro .
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2016, 117 :140-149
12345