A Rapidly Developing Nodule in a Patient With Hairy Cell Leukemia in Remission: Merkel Cell Carcinoma: A Case Report

被引：0

作者：

Sachanas, Sotirios ^{[1
]}

Stefanaki, Christina ^{[2
]}

Marinos, Leonidas ^{[3
]}

Yiakoumis, Xanthi ^{[1
]}

Moschogiannis, Maria ^{[1
]}

Koulieris, Efstathios ^{[1
]}

Efstathopoulou, Maria ^{[1
]}

Pangalis, Gerassimos a. ^{[1
]}

机构：

[1] Athens Med Ctr, Dept Hematol, Psychikon Branch, Andersen 1, Athens 11525, Greece

[2] Athens Med Ctr, Psychikon Branch, Athens, Greece

[3] Evangelismos Gen Hosp, Dept Hematopathol, Athens, Greece

来源：

IN VIVO | 2024年 / 38卷 / 05期

关键词：

Hairy cell leukemia; Merkel cell carcinoma; pentostatin; immunosuppression; CHRONIC LYMPHOCYTIC-LEUKEMIA; INFECTION; DIAGNOSIS; RISK;

D O I：

10.21873/invivo.13727

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Background/Aim: Hairy cell leukemia (HCL) is a well-known lymphoproliferative disease with very effective treatment approaches primarily relying on purine analogues. However, these treatments are associated with profound and is a rare and extremely aggressive skin tumor with an increased incidence in immunocompromised patients. Case Report: We report a case of a patient with HCL who was diagnosed with MCC, while in remission following retreatment with pentostatin, which induced a profound decrease in CD4 supporting the hypothesis of a significant association between immunosuppression and MCC pathogenesis.

引用

页码：2540 / 2544

页数：5

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