A Rapidly Developing Nodule in a Patient With Hairy Cell Leukemia in Remission: Merkel Cell Carcinoma: A Case Report

被引：0
作者：
Sachanas, Sotirios [1 ]
Stefanaki, Christina [2 ]
Marinos, Leonidas [3 ]
Yiakoumis, Xanthi [1 ]
Moschogiannis, Maria [1 ]
Koulieris, Efstathios [1 ]
Efstathopoulou, Maria [1 ]
Pangalis, Gerassimos a. [1 ]
机构：
[1] Athens Med Ctr, Dept Hematol, Psychikon Branch, Andersen 1, Athens 11525, Greece
[2] Athens Med Ctr, Psychikon Branch, Athens, Greece
[3] Evangelismos Gen Hosp, Dept Hematopathol, Athens, Greece
来源：
IN VIVO | 2024年 / 38卷 / 05期
关键词：
Hairy cell leukemia; Merkel cell carcinoma; pentostatin; immunosuppression; CHRONIC LYMPHOCYTIC-LEUKEMIA; INFECTION; DIAGNOSIS; RISK;
D O I：
10.21873/invivo.13727
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Background/Aim: Hairy cell leukemia (HCL) is a well-known lymphoproliferative disease with very effective treatment approaches primarily relying on purine analogues. However, these treatments are associated with profound and is a rare and extremely aggressive skin tumor with an increased incidence in immunocompromised patients. Case Report: We report a case of a patient with HCL who was diagnosed with MCC, while in remission following retreatment with pentostatin, which induced a profound decrease in CD4 supporting the hypothesis of a significant association between immunosuppression and MCC pathogenesis.
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收藏
页码：2540 / 2544
页数：5
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