Initial surgery for spontaneous intestinal perforation in extremely low birth weight infants is not associated with mortality or in-hospital morbidities

被引：0

作者：

Hair, Amy B. ^{[1
]}

Sullivan, Kevin M. ^{[2
,3
]}

Ahmad, Irfan ^{[4
]}

Zaniletti, Isabella ^{[5
]}

Acker, Shannon N. ^{[6
]}

Premkumar, Muralidhar H. ^{[1
]}

Reber, Kristina ^{[1
]}

Huff, Katie A. ^{[7
]}

Nayak, Sujir Pritha ^{[8
]}

Digeronimo, Robert ^{[9
]}

Kim, Jae ^{[10
]}

Roberts, Jessica ^{[11
]}

Markel, Troy A. ^{[7
]}

Brozanski, Beverly ^{[12
]}

Sharma, Jotishna ^{[13
]}

Piazza, Anthony J. ^{[11
]}

Yanowitz, Toby D. ^{[14
]}

机构：

[1] Texas Childrens Hosp, Baylor Coll Med, Houston, TX 77030 USA

[2] Thomas Jefferson Univ, Sidney Kimmel Med Coll, Philadelphia, PA USA

[3] Nemours Childrens Hosp, Wilmington, DE USA

[4] Childrens Hosp Orange Cty, Orange, CA USA

[5] Childrens Hosp Assoc, Lenexa, KS USA

[6] Univ Colorado, Childrens Hosp Colorado, Aurora, CO USA

[7] Indiana Univ Sch Med, Riley Hosp Children, Indianapolis, IN USA

[8] Univ Texas Southwestern Med Ctr, Dallas, TX USA

[9] Univ Washington, Seattle Childrens Hosp, Seattle, WA USA

[10] Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH USA

[11] Emory Univ, Sch Med, Childrens Healthcare Atlanta, Atlanta, GA USA

[12] Washington Univ, Sch Med, St Louis Childrens Hosp, St Louis, MO USA

[13] Missouri Univ, Childrens Mercy Hosp, Missouri Kansas City Sch Med, Kansas City, MO USA

[14] Univ Pittsburgh, Sch Med, UPMC Childrens Hosp Pittsburgh, Pittsburgh, PA USA

来源：

JOURNAL OF PERINATOLOGY | 2024年 / 44卷 / 12期

关键词：

NECROTIZING ENTEROCOLITIS; NEURODEVELOPMENTAL OUTCOMES; PERITONEAL DRAINAGE; MANAGEMENT; GROWTH; CARE;

D O I：

10.1038/s41372-024-02037-8

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

OBJECTIVE: Determine short-term outcomes following peritoneal drain (PD), laparotomy (LAP) after PD (PD-LAP), and LAP in extremely low birth weight (ELBW) infants with spontaneous intestinal perforation (SIP). STUDY DESIGN: ELBW infants with SIP were identified using the Children's Hospitals Neonatal Database. Mortality and length of stay (LOS) were compared among groups. RESULTS: Of 729 SIP infants from 6/2010-12/2016, 383(53%) received PD, 61(8%) PD-LAP, and 285(39%) LAP. PD infants had lower GA at birth, at SIP diagnosis and upon admission than PD-LAP or LAP; and higher sepsis rates than LAP. Bivariate analysis and Kaplan-Meier survival estimates suggested PD had increased mortality vs. PD-LAP and LAP (27%, 11.5%, and 15.8% respectively, p < 0.001). However, surgical approach was not significantly associated with mortality in multivariable analysis accounting for GA and illness severity. LOS did not differ by surgical approach. CONCLUSIONS: In ELBW infants with SIP, mortality, and LOS are independent of the initial surgical approach.

引用

页码：1746 / 1754

页数：9

共 21 条

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