Autogenous Bilateral Cleft Alveolar Bone Grafting with rhBMP-2 and Cellular Bone Matrix

被引：1
作者：
Harrison, Lucas M. [1 ]
Hallac, Rami R. [1 ,2 ]
Seaward, James [1 ]
Kane, Alex A. [1 ]
Park, Yong-Jong [3 ]
机构：
[1] Univ Texas Southwestern Med Ctr, Dept Plast Surg, Dallas, TX USA
[2] Childrens Med Ctr, Analyt Imaging & Modeling Ctr, Dallas, TX USA
[3] Childrens Med Ctr, Dept Orthodont, Dallas, TX USA
来源：
CLEFT PALATE CRANIOFACIAL JOURNAL | 2024年
关键词：
cleft lip and palate; surgical technique; allographs; bone grafting; COMPUTED-TOMOGRAPHY; OUTCOMES; MORBIDITY; PROTEIN-2;
D O I：
10.1177/10556656241271672
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Alveolar bone grafting (ABG) in bilateral cleft lip and palate (BCLP) patients provides a reconstructive challenge. We present a novel technique of combining autologous iliac crest bone graft (ICBG) with recombinant human bone morphogenic protein 2 (rhBMP-2) and cellular bone matrix (CBM) for ABG in BCLP patients. Complete bone fill occurred in 90% of patients, with 100% having bilateral canine eruption. No patients required repeat ABG, and no significant complications were reported. The alveolar cleft gap volume significantly decreased with an improvement of 75.87%. ABG with autologous ICBG with rhBMP-2 and CBM is an effective technique for patients with BCLP.
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页数：4
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