Bio-properties of Mg-RE alloys: an applied study on cytotoxicity and genotoxicity

被引:0
作者
Djebari, Kenza [1 ]
Turen, Yunus [1 ]
Elen, Levent [1 ]
Ahlatci, Hayrettin [1 ]
Bozer, Busra Moran [2 ]
Cicek, Bunyamin [3 ]
机构
[1] Karabuk Univ, Fac Engn, Dept Met & Mat Engn, Karabuk, Turkiye
[2] Hitit Univ, Sci Tech Applicat & Res Ctr, Corum, Turkiye
[3] Hitit Univ, Tech Sci Vocat Coll, Corum, Turkiye
关键词
Mg-RE alloys; rare elements; biocompatibility; cytotoxicity; genotoxicity; BIODEGRADABLE MAGNESIUM ALLOYS; ZN-Y ALLOYS; MECHANICAL-PROPERTIES; CORROSION-RESISTANCE; RARE-EARTH; IN-VITRO; PROFILE ANALYSIS; MICROSTRUCTURE; GD; BIOCOMPATIBILITY;
D O I
10.1080/00084433.2024.2397190
中图分类号
TF [冶金工业];
学科分类号
0806 ;
摘要
This study presents a comprehensive review of magnesium alloys with rare elements. It discusses Mg-RE alloys and includes an experimental process. Thus, the data obtained by examining Mg-RE alloys provided a better interpretation of the experimental study. In this study's investigation report, Mg-RE alloys were thoroughly analyzed. In the experimental part, the cytotoxic and genotoxic results of the rare elements added to the Mg-Zn-RE master alloy are discussed. Experiments were carried out by adding Nd and Ce to this master alloy in inverse proportions. In cytotoxic data, it was observed that the viability rate in bacteria increased by up to 200%. In addition, significant genotoxic results of Mg-RE alloys were obtained, which are uncommon in the literature. As a result, a new perspective on Mg-RE alloys has been created. Cette & eacute;tude pr & eacute;sente un examen complet des alliages de magn & eacute;sium contenant des & eacute;l & eacute;ments rares. Elle discute des alliages Mg-ER et comprend un proc & eacute;d & eacute; exp & eacute;rimental. Ainsi, les donn & eacute;es obtenues en examinant les alliages Mg-ER ont fourni une meilleure interpr & eacute;tation de l'& eacute;tude exp & eacute;rimentale. Dans le rapport d'investigation de cette & eacute;tude, on a analys & eacute; & agrave; fond les alliages Mg-ER. Dans la partie exp & eacute;rimentale, on discute des r & eacute;sultats cytotoxiques et g & eacute;notoxiques des & eacute;l & eacute;ments rares ajout & eacute;s & agrave; l'alliage m & egrave;re Mg-Zn-ER. On a r & eacute;alis & eacute; des exp & eacute;riences en ajoutant du Nd et du Ce & agrave; cet alliage m & egrave;re en proportions inverses. Dans les donn & eacute;es cytotoxiques, on a observ & eacute; que le taux de viabilit & eacute; des bact & eacute;ries a augment & eacute; jusqu'& agrave; 200%. De plus, on a obtenu des r & eacute;sultats g & eacute;notoxiques significatifs des alliages Mg-ER, qui sont peu communs dans la litt & eacute;rature. Par cons & eacute;quent, on a cr & eacute;& eacute; une nouvelle perspective sur les alliages Mg-ER.
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页数:13
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共 92 条
  • [1] Biodegradable magnesium alloys for orthopaedic applications: A review on corrosion, biocompatibility and surface modifications
    Agarwal, Sankalp
    Curtin, James
    Duffy, Brendan
    Jaiswal, Swarna
    [J]. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2016, 68 : 948 - 963
  • [2] p(thyme oil) and p(clove oil) organo-particles with biocompatible, anticancer, antioxidant, and antibacterial properties against Capan-1 and L-929 cells
    Alpaslan, Duygu
    Dudu, Tuba Ersen
    Bozer, Busra Moran
    Aktas, Nahit
    Turk, Mustafa
    [J]. CANADIAN JOURNAL OF CHEMICAL ENGINEERING, 2024, 102 (01) : 76 - 87
  • [3] Biodegradable magnesium-based biomaterials: An overview of challenges and opportunities
    Amukarimi, Shukufe
    Mozafari, Masoud
    [J]. MEDCOMM, 2021, 2 (02): : 123 - 144
  • [4] Magnesium-based alloys with adapted interfaces for bone implants and tissue engineering
    Antoniac, Iulian
    Manescu , Veronica
    Antoniac, Aurora
    Paltanea, Gheorghe
    [J]. REGENERATIVE BIOMATERIALS, 2023, 10
  • [5] Comparative Assessment of In Vitro and In Vivo Biodegradation of Mg-1Ca Magnesium Alloys for Orthopedic Applications
    Antoniac, Iulian
    Adam, Razvan
    Bita, Ana
    Miculescu, Marian
    Trante, Octavian
    Petrescu, Ionut Mircea
    Pogarasteanu, Mark
    [J]. MATERIALS, 2021, 14 (01) : 1 - 20
  • [6] X-RAY INVESTIGATION OF AGEING IN AN ALUMINIUM-5 PERCENT MAGNESIUM ALLOY WITH SMALL SILVER ADDITIONS
    AULD, JH
    [J]. ACTA METALLURGICA, 1968, 16 (01): : 97 - &
  • [7] A Systematic Review of the Genotoxicity and Antigenotoxicity of Biologically Synthesized Metallic Nanomaterials: Are Green Nanoparticles Safe Enough for Clinical Marketing?
    Barabadi, Hamed
    Najafi, Masoud
    Samadian, Hadi
    Azarnezhad, Asaad
    Vahidi, Hossein
    Mahjoub, Mohammad Ali
    Koohiyan, Mahbobeh
    Ahmadi, Amirhossein
    [J]. MEDICINA-LITHUANIA, 2019, 55 (08):
  • [8] In Vitro and in Vivo Studies on Biomedical Magnesium Low-Alloying with Elements Gadolinium and Zinc for Orthopedic Implant Applications
    Bian, Dong
    Deng, Jiuxu
    Li, Nan
    Chu, Xiao
    Liu, Yang
    Li, Wenting
    Cai, Hong
    Xiu, Peng
    Zhang, Yu
    Guan, Zhenpeng
    Zheng, Yufeng
    Kou, Yuhui
    Jiang, Baoguo
    Chen, Rongshi
    [J]. ACS APPLIED MATERIALS & INTERFACES, 2018, 10 (05) : 4394 - 4408
  • [9] Birca AC, 2018, ROM J MORPHOL EMBRYO, V59, P49
  • [10] Development of a new magnesium alloy ZW21
    Chen, T. J.
    Wang, W.
    Zhang, D. H.
    Ma, Y.
    Hao, Y.
    [J]. MATERIALS & DESIGN, 2013, 44 : 555 - 565