Low LDL-C: Is It all Good News?

被引：0

作者：

Hartz, Jacob ^{[1
]}

机构：

[1] Boston Childrens Hosp, 300 Longwood Ave, Boston, MA 02115 USA

来源：

CURRENT ATHEROSCLEROSIS REPORTS | 2024年 / 26卷 / 12期

基金：

美国国家卫生研究院;

关键词：

Hypobetalipoproteinemia; Lipid-lowering therapy; Atherosclerotic cardiovascular disease; Adverse effects; LOW-DENSITY-LIPOPROTEIN; FAMILIAL COMBINED HYPOLIPIDEMIA; VERY-LOW LEVELS; STATIN THERAPY; HEMORRHAGIC STROKE; APO-B; TOO LOW; CHOLESTEROL; RISK; SAFETY;

D O I：

10.1007/s11883-024-01238-y

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Purpose of reviewThis review presents the risks and benefits of very low LDL cholesterol and the safety of using lipid-lowering therapy to achieve these levels.Recent findingsA growing body of literature suggests that lower LDL cholesterol levels are associated with a reduced risk of cardiovascular disease. Further, achieving these levels with pharmaceuticals is remarkably safe. Although statins may slightly increase the risk of diabetes mellitus and hemorrhagic stroke, the benefits outweigh the risks.SummaryWhile recommendations from professional societies are increasingly aggressive, additional risk reduction could be achieved by setting more even ambitious LDL cholesterol goals.

引用

页码：673 / 681

页数：9

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