Gastric cancer and brain metastasis: A systematic review and meta-analysis

被引：0

作者：

Fotakopoulos, George ^{[1
]}

Christodoulidis, Grigorios ^{[2
]}

Georgakopoulou, Vasiliki Epameinondas ^{[3
]}

Trakas, Nikolaos ^{[4
]}

Skapani, Pagona ^{[4
]}

Panagiotopoulos, Konstantinos ^{[5
]}

Spandidos, Demetrios A. ^{[6
]}

Foroglou, Nicolas ^{[7
]}

机构：

[1] Gen Univ Hosp Larisa, Dept Neurosurg, Mezourlo 1, Larisa 41221, Greece

[2] Gen Univ Hosp Larisa, Dept Gen Surg, Mezourlo 41221, Larisa, Greece

[3] Natl & Kapodistrian Univ Athens, Dept Pathophysiol, Athens 11527, Greece

[4] Sismanogleio Hosp, Dept Biochem, Athens 15126, Greece

[5] Gen Hosp Athens Georgios Gennimatas, Biochem Lab, Athens 11527, Greece

[6] Univ Crete, Sch Med, Lab Clin Virol, Iraklion 71003, Greece

[7] Aristotle Univ Thessaloniki, AHEPA Univ Hosp, Dept Neurosurg 1, Thessaloniki 54636, Greece

来源：

MOLECULAR AND CLINICAL ONCOLOGY | 2024年 / 21卷 / 05期

关键词：

gastric cancer; brain metastasis; surgical resection; survival outcomes; conservative or no-surgical treatment;

D O I：

10.3892/mco.2024.2775

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Gastric cancer (GC) constitutes one of the most wide-ranging cancers, with brain metastasis (BM) being a markedly uncommon and unfavorable outcome. The present meta-analysis evaluated the relationship between no-surgical treatment vs. additional surgical BM resection on the patient's quality of life and potential survival using electronic databases, including PubMed (1980-April 2024), Medline (1980-April 2024), Cochrane Library, and EMBASE (1980-April 2024). After a literature search, six articles were included in the final study pool. The number of patients with BM and conservative treatment was 289 (80.05%) compared with those that underwent an additional surgical resection 72 (19.95%). The mean age was 59.2 years, and the males were 195 (73.8%) of 264 available from five studies. The findings of the present meta-analysis revealed that the curative effect of BM tumor resection on patients with GC undergoing additional treatment with stereotactic radiosurgery, whole-brain radiotherapy or chemotherapy was favorable for their survival.

引用

页数：6

共 23 条

[1]

ABRAMS HL, 1950, CANCER, V3, P74, DOI 10.1002/1097-0142(1950)3:1<74::AID-CNCR2820030111>3.0.CO

[2]

2-7

[3] Population, Intervention, Comparison, Outcomes and Study (PICOS) design as a framework to formulate eligibility criteria in systematic reviews [J].

Amir-Behghadami, Mehrdad ;

Janati, Ali .

EMERGENCY MEDICINE JOURNAL, 2020, 37 (06) :387-387

[4] A suggestion for quality assessment in systematic reviews of observational studies in nutritional epidemiology [J].

Bae, Jong-Myon .

EPIDEMIOLOGY AND HEALTH, 2016, 38 :e2016014

[5] Toward determining the lifetime occurrence of metastatic brain tumors estimated from 2007 United States cancer incidence data [J].

Davis, Faith G. ;

Dolecek, Therese A. ;

McCarthy, Bridget J. ;

Villano, John L. .

NEURO-ONCOLOGY, 2012, 14 (09) :1171-1177

[6] Investigation of the recurrence patterns of gastric cancer following a curative resection [J].

Deng, Jingyu ;

Liang, Han ;

Wang, Dianchang ;

Sun, Dan ;

Pan, Yi ;

Liu, Yong .

SURGERY TODAY, 2011, 41 (02) :210-215

[7] Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017 A Systematic Analysis for the Global Burden of Disease Study [J].

Fitzmaurice, Christina ;

Abate, Degu ;

Abbasi, Naghmeh ;

Abbastabar, Hedayat ;

Abd-Allah, Foad ;

Abdel-Rahman, Omar ;

Abdelalim, Ahmed ;

Abdoli, Amir ;

Abdollahpour, Ibrahim ;

Abdulle, Abdishakur S. M. ;

Abebe, Nebiyu Dereje ;

Abraha, Haftom Niguse ;

Abu-Raddad, Laith Jamal ;

Abualhasan, Ahmed ;

Adedeji, Isaac Akinkunmi ;

Advani, Shailesh M. ;

Afarideh, Mohsen ;

Afshari, Mandi ;

Aghaali, Mohammad ;

Agius, Dominic ;

Agrawal, Sutapa ;

Ahmadi, Ayat ;

Ahmadian, Elham ;

Ahmadpour, Ehsan ;

Ahmed, Muktar Beshir ;

Akbari, Mohammad Esmaeil ;

Akinyemiju, Tomi ;

Al-Aly, Ziyad ;

AlAbdulKader, Assim M. ;

Alandab, Fares ;

Alam, Tahiya ;

Alamene, Genet Melak ;

Alemnew, Birhan Tamene T. ;

Alene, Kefyalew Addis ;

Alinia, Cyrus ;

Alipour, Vahid ;

Aljunid, Syed Mohamed ;

Bakeshei, Fatemeh Allah ;

Abdulrahman, Majid ;

Almadi, Hamad ;

Almasi-Hashiani, Amir ;

Alsharif, Ubai ;

Alsowaidi, Shirina ;

Alvis-Guzman, Nelson ;

Amini, Erfan ;

Amini, Saeed ;

Amoako, Yaw Ampem ;

Anbari, Zohreh ;

Anber, Nahla Hamed ;

Andrei, Catalina Liliana .

JAMA ONCOLOGY, 2019, 5 (12) :1749-1768

[8] Reporting guidelines: CONSORT, PRISMA, and SQUIRE [J].

Foster, Roxie L. .

JOURNAL FOR SPECIALISTS IN PEDIATRIC NURSING, 2012, 17 (01) :1-2

[9] Recursive partitioning analysis (RPA) of prognostic factors in three radiation therapy oncology group (RTOG) brain metastases trials [J].

Gaspar, L ;

Scott, C ;

Rotman, M ;

Asbell, S ;

Phillips, T ;

Wasserman, T ;

McKenna, WG ;

Byhardt, R .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1997, 37 (04) :745-751

[10] A comprehensive evaluation of clinical efficacy and safety of celecoxib in combination with chemotherapy in metastatic or postoperative recurrent gastric cancer patients A preliminary, three-center, clinical trial study [J].

Guo, Qinghong ;

Li, Qiang ;

Wang, Jiong ;

Liu, Min ;

Wang, Yuping ;

Chen, Zhaofeng ;

Ye, Yuwei ;

Guan, Quanlin ;

Zhou, Yongning .

MEDICINE, 2019, 98 (27)

← 1 2 3 →