ChCl:Urea deep eutectic solvent as a green media for one-pot, three-component catalyst-free synthesis of spiro-benzoxazole derivatives

被引：1

作者：

Asilpour, Fatemeh ^{[1
]}

Saberi, Dariush ^{[1
]}

Hasaninejad, Alireza ^{[1
]}

机构：

[1] Persian Gulf Univ, Fac Nano & Bio Sci & Technol, Dept Chem, Bushehr 75169, Iran

来源：

JOURNAL OF MOLECULAR LIQUIDS | 2024年 / 409卷

关键词：

Deep eutectic solvent; Choline chloride; Catalyst-free; Isatin; Dihydrobenzoxazole; Spiro-benzoxazoles; EFFICIENT; DIHYDROPYRIDINES; DESS;

D O I：

10.1016/j.molliq.2024.125537

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

An efficient catalyst-free procedure is reported for the one-pot three-component synthesis of novel spirobenzoxazole derivatives via the condensation reaction of isatins, dihydrobenzoxazole compounds, and malono derivatives in ChCl:Urea deep eutectic solvent, as a green reaction medium. Spiro-benzoxazoles were easily extracted from the reaction mixture, by adding water, and isolated in good to excellent yields.

引用

页数：6

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