Reduction of RNA-Editing Enzyme ADAR1 in Human Islets Triggers an Interferon Response and Impairs Beta-Cell Function

被引:0
|
作者
Dai, Chunhua
Singh, Ajay K.
Brantley, Rebekah
Bradley, Amber
Jenkins, Regina
Saunders, Diane C.
Brissova, Marcela
Levanon, Erez
Klochendler, Agnes
Dor, Yuval
Powers, Alvin C.
机构
关键词
D O I
10.2337/db24-349-OR
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
349-OR
引用
收藏
页数:2
相关论文
共 50 条
  • [31] The snoRNA-like lncRNA LNC-SNO49AB drives leukemia by activating the RNA-editing enzyme ADAR1
    Wei Huang
    Yu-Meng Sun
    Qi Pan
    Ke Fang
    Xiao-Tong Chen
    Zhan-Cheng Zeng
    Tian-Qi Chen
    Shun-Xin Zhu
    Li-Bin Huang
    Xue-Qun Luo
    Wen-Tao Wang
    Yue-Qin Chen
    Cell Discovery, 8
  • [32] RNA editing enzyme ADAR1 accelerates normal hematopoiesis cell cycle by regulation microRNA biogenesis
    Jiang, Qingfei
    Zipeto, Maria Anna
    Delos Santos, Nathan
    Morris, Sheldon
    Jamieson, Catriona
    CANCER RESEARCH, 2017, 77
  • [33] RNA Editing Enzyme ADAR1 Accelerates Normal Hematopoiesis Cell Cycle By Regulating microRNA Biogenesis
    Jiang, Qingfei
    Zipeto, Maria A.
    Delos Santos, Nathaniel
    Leu, Heather
    Isquith, Jane
    Atien, Etienne
    Jamieson, Catriona
    BLOOD, 2016, 128 (22)
  • [34] Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis
    C Anadón
    S Guil
    L Simó-Riudalbas
    C Moutinho
    F Setien
    A Martínez-Cardús
    S Moran
    A Villanueva
    M Calaf
    A Vidal
    P A Lazo
    I Zondervan
    S Savola
    T Kohno
    J Yokota
    L Ribas de Pouplana
    M Esteller
    Oncogene, 2016, 35 : 4407 - 4413
  • [35] Publisher Correction: Dynamic regulation of Z-DNA in the mouse prefrontal cortex by the RNA-editing enzyme Adar1 is required for fear extinction
    Paul R. Marshall
    Qiongyi Zhao
    Xiang Li
    Wei Wei
    Ambika Periyakaruppiah
    Esmi L. Zajaczkowski
    Laura J. Leighton
    Sachithrani U. Madugalle
    Dean Basic
    Ziqi Wang
    Jiayu Yin
    Wei-Siang Liau
    Ankita Gupte
    Carl R. Walkley
    Timothy W. Bredy
    Nature Neuroscience, 2020, 23 : 1034 - 1034
  • [36] Nucleocytoplasmic distribution of human RNA-editing enzyme ADAR1 is modulated by double-stranded RNA-binding domains, a leucine-rich export signal, and a putative dimerization domain
    Strehblow, A
    Hallegger, M
    Jantsch, MF
    MOLECULAR BIOLOGY OF THE CELL, 2002, 13 (11) : 3822 - 3835
  • [37] Ribonuclease L mediates the cell-lethal phenotype of double-stranded RNA editing enzyme ADAR1 deficiency in a human cell line
    Li, Yize
    Banerjee, Shuvojit
    Goldstein, Stephen A.
    Dong, Beihua
    Gaughan, Christina
    Rath, Sneha
    Donovan, Jesse
    Korennykh, Alexei
    Silverman, Robert H.
    Weiss, Susan R.
    ELIFE, 2017, 6
  • [38] Erratum: Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis
    C Anadón
    S Guil
    L Simó-Riudalbas
    C Moutinho
    F Setien
    A Martínez-Cardús
    S Moran
    A Villanueva
    M Calaf
    A Vidal
    P A Lazo
    I Zondervan
    S Savola
    T Kohno
    J Yokota
    L Ribas de Pouplana
    M Esteller
    Oncogene, 2016, 35 : 4422 - 4422
  • [39] RNA editing enzyme ADAR1 is required for early T cell development (Vol 2, Pg 27, 2020)
    Xufeng, Richard
    Nie, Daibang
    Yang, Qiong
    Wang, Wang
    Cheng, Tao
    Wang, Qingde
    BLOOD SCIENCE, 2021, 3 (03):
  • [40] Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development
    Pestal, Kathleen
    Funk, Cory C.
    Snyder, Jessica M.
    Price, Nathan D.
    Treuting, Piper M.
    Stetson, Daniel B.
    IMMUNITY, 2015, 43 (05) : 933 - 944