Incidence and Risk Factors for Invasive Fungal Infections in Patients Initiating Tumor Necrosis Factor-Alpha Inhibitors for Inflammatory Bowel Disease and Rheumatoid Arthritis

被引：3
作者：
Hennessee, Ian [1 ,2 ]
Benedict, Kaitlin [1 ]
Bahr, Nathan C. [3 ]
Lipner, Shari R. [4 ]
Gold, Jeremy A. W. [1 ]
机构：
[1] CDCP, Mycot Dis Branch, 1600 Clifton Rd NE,Mailstop H24-11, Atlanta, GA 30329 USA
[2] CDCP, Epidem Intelligence Serv, Atlanta, GA USA
[3] Univ Minnesota, Div Infect Dis & Int Med, Minneapolis, MN USA
[4] Weill Cornell Med, Dept Dermatol, New York, NY USA
来源：
CLINICAL INFECTIOUS DISEASES | 2024年 / 80卷 / 02期
基金：
美国国家卫生研究院;
关键词：
TNF-alpha inhibitors; inflammatory bowel disease; rheumatoid arthritis; invasive fungal infections; histoplasmosis; SERIOUS INFECTIONS; THERAPY; METAANALYSIS;
D O I：
10.1093/cid/ciae444
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
In a commercial claims database analysis, <0.5% of patients with inflammatory bowel disease or rheumatoid arthritis developed an invasive fungal infection (IFI) within 1 year of initiating tumor necrosis factor-alpha therapy. Histoplasmosis was the most common IFI type. Overall IFI incidence varied based on region, underlying conditions, and use of certain immunosuppressive medications.
引用
收藏
页码：364 / 366
页数：3
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