Incidence and Risk Factors for Invasive Fungal Infections in Patients Initiating Tumor Necrosis Factor-Alpha Inhibitors for Inflammatory Bowel Disease and Rheumatoid Arthritis

被引：3
|
作者：
Hennessee, Ian [1 ,2 ]
Benedict, Kaitlin [1 ]
Bahr, Nathan C. [3 ]
Lipner, Shari R. [4 ]
Gold, Jeremy A. W. [1 ]
机构：
[1] CDCP, Mycot Dis Branch, 1600 Clifton Rd NE,Mailstop H24-11, Atlanta, GA 30329 USA
[2] CDCP, Epidem Intelligence Serv, Atlanta, GA USA
[3] Univ Minnesota, Div Infect Dis & Int Med, Minneapolis, MN USA
[4] Weill Cornell Med, Dept Dermatol, New York, NY USA
来源：
CLINICAL INFECTIOUS DISEASES | 2024年 / 80卷 / 02期
基金：
美国国家卫生研究院;
关键词：
TNF-alpha inhibitors; inflammatory bowel disease; rheumatoid arthritis; invasive fungal infections; histoplasmosis; SERIOUS INFECTIONS; THERAPY; METAANALYSIS;
D O I：
10.1093/cid/ciae444
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
In a commercial claims database analysis, <0.5% of patients with inflammatory bowel disease or rheumatoid arthritis developed an invasive fungal infection (IFI) within 1 year of initiating tumor necrosis factor-alpha therapy. Histoplasmosis was the most common IFI type. Overall IFI incidence varied based on region, underlying conditions, and use of certain immunosuppressive medications.
引用
收藏
页码：364 / 366
页数：3
相关论文
共 50 条
  • [1] RISK OF INVASIVE FUNGAL INFECTIONS WITH TUMOR NECROSIS FACTOR-ALPHA INHIBITORS AND CORTICOSTEROIDS AMONG PATIENTS WITH INFLAMMATORY BOWEL DISEASE
    Gregory, Martin H.
    Spec, Andrej
    Stwalley, Dustin
    Gremida, Anas K.
    Mejia-Chew, Carlos
    Nickel, Katelin B.
    Ciorba, Matthew A.
    Rood, Richard P.
    Olsen, Margaret A.
    Deepak, Parakkal
    GASTROENTEROLOGY, 2022, 162 (07) : S7 - S8
  • [2] Corticosteroids Increase the Risk of Invasive Fungal Infections More Than Tumor Necrosis Factor-Alpha Inhibitors in Patients With Inflammatory Bowel Disease
    Gregory, Martin H.
    Spec, Andrej
    Stwalley, Dustin
    Gremida, Anas
    Mejia-Chew, Carlos
    Nickel, Katelin B.
    Ciorba, Matthew A.
    Rood, Richard P.
    Olsen, Margaret A.
    Deepak, Parakkal
    CROHNS & COLITIS 360, 2023, 5 (02)
  • [3] Low incidence of invasive fungal infection and risk factors in a large observational cohort of patients initiating tumor necrosis factor-alpha inhibitors for dermatologic conditions
    Hennessee, Ian
    Benedict, Kaitlin
    Bahr, Nathan C.
    Lipner, Shari R.
    Gold, Jeremy A. W.
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2024, 91 (03) : 510 - 513
  • [4] Dermatoses in patients with inflammatory bowel disease under tumor necrosis factor-alpha inhibitors treatment
    Magalhaes, Carolina Mundim Couto
    Bartholo, Marina Ribeiro
    Correa, Bernardo Henrique Mendes
    Ferrari, Maria de Lourdes Abreu
    Ferrari, Teresa Cristina Abreu
    MEDICINA CLINICA, 2025, 164 (04): : 173 - 177
  • [5] Tumor Necrosis Factor-Alpha Inhibitors and Cardiovascular Risk in Rheumatoid Arthritis: A Systematic Review
    Nair, Shaalina
    Kahlon, Simranjit Singh
    Sikandar, Rabia
    Peddemul, Aishwarya
    Tejovath, Sreedevi
    Hassan, Danial
    Patel, Khushbu K.
    Mostafa, Jihan A.
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2022, 14 (06)
  • [6] Risk of Myeloid Neoplasms in Inflammatory Bowel Disease Patients Is Linked to Exposure to Thiopurines and Not With Tumor Necrosis Factor-alpha Inhibitors
    Deepak, Parakkal
    Stobaugh, Derrick J.
    CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2015, 13 (10) : 1857 - 1858
  • [7] The safety of tumor necrosis factor-alpha inhibitors in the treatment of rheumatoid arthritis
    Victoria Hernandez, Maria
    Sanmarti, Raimon
    Canete, Juan D.
    EXPERT OPINION ON DRUG SAFETY, 2016, 15 (05) : 613 - 624
  • [8] Characterization of the treatment of rheumatoid arthritis for patients prescribed tumor necrosis factor-alpha inhibitors
    Stockl, K
    Jarrar, M
    Tandon, N
    VALUE IN HEALTH, 2004, 7 (03) : 245 - 245
  • [9] Histoplasmosis in Inflammatory Bowel Disease with Tumor Necrosis Factor-Alpha Inhibitors: Safe to Continue Biologics?
    Jansson-Knodell, Claire L.
    Harris, Courtney E.
    Loftus, Edward V., Jr.
    Walker, Randall C.
    Enzler, Mark J.
    Virk, Abinash
    DIGESTIVE DISEASES AND SCIENCES, 2021, 66 (01) : 190 - 198
  • [10] Histoplasmosis in Inflammatory Bowel Disease with Tumor Necrosis Factor-Alpha Inhibitors: Safe to Continue Biologics?
    Claire L. Jansson-Knodell
    Courtney E. Harris
    Edward V. Loftus
    Randall C. Walker
    Mark J. Enzler
    Abinash Virk
    Digestive Diseases and Sciences, 2021, 66 : 190 - 198
12345