Global Burden of Inflammatory Bowel Disease Among Children and Adolescents: A Comprehensive Analysis (1990-2019)

被引：2

作者：

Chen, Xuejie ^{[1
]}

Xiang, Xin ^{[1
]}

Fan, Xiaofei ^{[2
]}

Xia, Weitong ^{[1
]}

Xiao, Yi ^{[1
]}

Wang, Sidan ^{[1
]}

Ye, Shuyu ^{[1
]}

Kang, Meng ^{[1
]}

Jing, Fangmin ^{[1
]}

Wu, Xing ^{[1
]}

Chen, Yang ^{[1
,3
]}

机构：

[1] Cent South Univ, Dept Gastroenterol, Xiangya Hosp 3, Changsha, Hunan, Peoples R China

[2] Shandong Med Coll, Dept Clin Med, Jinan, Shandong, Peoples R China

[3] Cent South Univ, Nursing Dept, Xiangya Hosp 3, Changsha, Hunan, Peoples R China

来源：

INTERNATIONAL JOURNAL OF PUBLIC HEALTH | 2024年 / 69卷

关键词：

mortality; trends; inflammatory bowel disease; global burden of disease; early-onset; NATURAL-HISTORY; CROHNS-DISEASE; GENETICS; TRENDS; ADULT; RISK;

D O I：

10.3389/ijph.2024.1607440

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Objective We summarize the global, regional, and national burden of inflammatory bowel disease (IBD) in children and adolescents from 1990 to 2019.Methods Based on the Global Burden of Disease Study 2019, the data of IBD in children and adolescents were analyzed by sex, age, year, and location. Joinpoint analysis was applied to assess the temporal trend of the disease burden.Results From 1990 to 2019, the incidence of IBD in children and adolescents increased by 22.8%, from 20,897.42 to 25,658.55 cases, especially in high SDI region. During the same period, the DALY numbers decreased by 53.5%, from 243,081.06 to 113,119.86, with all SDI regions experiencing a clear drop in DALYs except high SDI regions. In 2019, early-onset IBD incidence and DALY numbers were reported at 2,053.52 (95% UI: 1,575.62 to 2,677.49) and 73,797.46 (95% UI: 43,655.86 to 105,998.63), respectively.Conclusion Early-onset IBD in children and adolescents remains a significant global health concern. The disease burden has not improved in developed countries over the past 30 years, highlighting the need for targeted interventions.

引用

页数：9

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