DIAGNOSTIC PERFORMANCE OF A POINT-OF-CARE MOLECULAR SYSTEM FOR THE DETECTION OF SARSCOV-2 IN PERU

被引：0
作者：
Puyen, Zully M. [1 ,2 ]
Araujo-Castillo, Roger [1 ]
Giraldo, Jorge [1 ]
Gutierrez, Karina [1 ]
Rojas-Serrano, Nancy [1 ]
机构：
[1] Inst Nacl Salud, Lima, Peru
[2] Univ Peruana Ciencias Aplicadas, Escuela Med, Lima, Peru
来源：
REVISTA PERUANA DE MEDICINA EXPERIMENTAL Y SALUD PUBLICA | 2024年 / 41卷 / 01期
关键词：
SARS-CoV-2; COVID-19; Molecular Diagnostic Techniques; PCR; Sensitivity and Specifici- ty; Peru;
D O I：
10.17843/rpmesp.2024.411.13046
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
The present study assessed the diagnostic performance of the Xpert (R) Xpress SARS-CoV-2 test in comparison with the Charit & eacute; protocol real-time RT PCR for the detection of SARS-CoV-2 in Peruvian patients. This was a diagnostic test study that included 100 nasal and pharyngeal swab samples. We obtained an overall concordance of 98.70% (95%CI: 92.98-99.97), with a kappa coefficient of 0.97 (95%CI: 0.861.00) and sensitivity and relative specificity rates of 100% and 96.15%, respectively. Additionally, the percentage of the area under the ROC curve was 98.08% in both cases, and an analytical specificity rate of 100% was obtained for the different respiratory viruses evaluated. In conclusion, the Xpert (R) Xpress SARS-CoV-2 test, by using nasal and pharyngeal swab samples, was highly sensitive and specific, and the kappa coefficient showed an excellent correlation when compared to the reference test.
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页码：76 / 82
页数：7
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