PPInterface: A Comprehensive Dataset of 3D Protein-Protein Interface Structures

被引：0

作者：

Abali, Zeynep ^{[1
]}

Aydin, Zeynep ^{[1
]}

Khokhar, Moaaz ^{[3
]}

Ates, Yigit Can ^{[3
]}

Gursoy, Attila ^{[3
]}

Keskin, Ozlem ^{[2
]}

机构：

[1] Koc Univ, Computat Sci & Engn Grad Program, TR-34450 Istanbul, Turkiye

[2] Koc Univ, Chem & Biol Engn, TR-34450 Istanbul, Turkiye

[3] Koc Univ, Comp Engn, TR-34450 Istanbul, Turkiye

来源：

JOURNAL OF MOLECULAR BIOLOGY | 2024年 / 436卷 / 17期

关键词：

Protein interfaces; Dataset; Protein-protein complexes; Protein-protein interactions; Interface visualization; 3D Protein-protein interface dataset; MOLECULAR-BIOLOGY; DATABASE; CLASSIFICATION;

D O I：

10.1016/j.jmb.2024.168686

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The PPInterface dataset contains 815,082 interface structures, providing the most comprehensive structural information on protein-protein interfaces. This resource is extracted from over 215,000 threedimensional protein structures stored in the Protein Data Bank (PDB). The dataset contains a wide range of protein complexes, providing a wealth of information for researchers investigating the structural properties of protein-protein interactions. The accompanying web server has a user-friendly interface that allows for efficient search and download functions. Researchers can access detailed information on protein interface structures, visualize them, and explore a variety of features, increasing the dataset's utility and accessibility. The dataset and web server can be found at https://3dpath.ku.edu.tr/PPInt/. (c) 2024 Published by Elsevier Ltd.

引用

页数：7

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