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PPInterface: A Comprehensive Dataset of 3D Protein-Protein Interface Structures
被引:0
|作者:
Abali, Zeynep
[1
]
Aydin, Zeynep
[1
]
Khokhar, Moaaz
[3
]
Ates, Yigit Can
[3
]
Gursoy, Attila
[3
]
Keskin, Ozlem
[2
]
机构:
[1] Koc Univ, Computat Sci & Engn Grad Program, TR-34450 Istanbul, Turkiye
[2] Koc Univ, Chem & Biol Engn, TR-34450 Istanbul, Turkiye
[3] Koc Univ, Comp Engn, TR-34450 Istanbul, Turkiye
关键词:
Protein interfaces;
Dataset;
Protein-protein complexes;
Protein-protein interactions;
Interface visualization;
3D Protein-protein interface dataset;
MOLECULAR-BIOLOGY;
DATABASE;
CLASSIFICATION;
D O I:
10.1016/j.jmb.2024.168686
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
The PPInterface dataset contains 815,082 interface structures, providing the most comprehensive structural information on protein-protein interfaces. This resource is extracted from over 215,000 threedimensional protein structures stored in the Protein Data Bank (PDB). The dataset contains a wide range of protein complexes, providing a wealth of information for researchers investigating the structural properties of protein-protein interactions. The accompanying web server has a user-friendly interface that allows for efficient search and download functions. Researchers can access detailed information on protein interface structures, visualize them, and explore a variety of features, increasing the dataset's utility and accessibility. The dataset and web server can be found at https://3dpath.ku.edu.tr/PPInt/. (c) 2024 Published by Elsevier Ltd.
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