Could Vaccination against COVID-19 Trigger Immune-Mediated Inflammatory Diseases?

被引：0

作者：

Liakou, Aikaterini I. ^{[1
]}

Tsantes, Andreas G. ^{[2
,3
]}

Routsi, Eleni ^{[1
]}

Agiasofitou, Efthymia ^{[1
]}

Kalamata, Magdalini ^{[1
]}

Bompou, Evangelia-Konstantina ^{[1
]}

Tsante, Konstantina A. ^{[2
]}

Vladeni, Soultana ^{[1
]}

Chatzidimitriou, Eleni ^{[1
]}

Kotsafti, Ourania ^{[1
]}

Samonis, George ^{[4
,5
]}

Bonovas, Stefanos ^{[6
,7
]}

Stratigos, Alexander I. ^{[1
]}

机构：

[1] Natl & Kapodistrian Univ Athens, Andreas Sygros Hosp, Med Sch, Dept Dermatol Venereol 1, Athens 16121, Greece

[2] Natl & Kapodistrian Univ Athens, Attikon Hosp, Med Sch, Lab Haematol & Blood Bank Unit, Athens 12462, Greece

[3] St Savvas Oncol Hosp, Microbiol Dept, Athens 11522, Greece

[4] Univ Crete, Dept Med, Iraklion 71500, Greece

[5] Metropolitan Hosp, Dept Oncol, Athens 18547, Greece

[6] Humanitas Univ, Dept Biomed Sci, I-20072 Milan, Italy

[7] IRCCS, Humanitas Res Hosp, Milan, Italy

来源：

JOURNAL OF CLINICAL MEDICINE | 2024年 / 13卷 / 16期

关键词：

immune-mediated inflammatory diseases; COVID-19; vaccine; flare; onset; hidradenitis;

D O I：

10.3390/jcm13164617

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Exacerbations and new onset of immune-mediated inflammatory diseases, such as psoriasis and hidradenitis suppurativa, have been reported following COVID-19 vaccination. In patients with hidradenitis suppurativa, recent studies have shown that those who received mRNA vaccines were 3.5 times as likely to develop flares following vaccination compared to patients who received non-mRNA vaccines, indicating that mRNA COVID-19 vaccines are associated with hidradenitis suppurativa flares. Similar findings have been found in other studies evaluating the association between COVID-19 vaccines and other immune-mediated inflammatory diseases such as psoriasis, atopic dermatitis, lichen planus, and alopecia areata. However, further research is warranted in larger populations to validate these findings.

引用

页数：10

共 56 条

[1]

Alexander Helen, 2022, JAAD Case Rep, V25, P13, DOI 10.1016/j.jdcr.2022.05.005

[2] Epstein-Barr Virus Infection and Multiple Sclerosis: A Review [J].

Ascherio, Alberto ;

Munger, Kassandra L. .

JOURNAL OF NEUROIMMUNE PHARMACOLOGY, 2010, 5 (03) :271-277

[3] Science commentary: Th1 and Th2 responses: what are they? [J].

Berger, A .

BRITISH MEDICAL JOURNAL, 2000, 321 (7258) :424-424

[4] Psoriasis flares after COVID-19 vaccination: adherence to biologic therapy reduces psoriasis exacerbations: a case-control study [J].

Burlando, Martina ;

Herzum, Astrid ;

Cozzani, Emanuele ;

Parodi, Aurora .

CLINICAL AND EXPERIMENTAL VACCINE RESEARCH, 2023, 12 (01) :80-81

[5] Efficacy and Safety of NVX-CoV2373 in Adults in the United States and Mexico [J].

Dunkle, Lisa M. ;

Kotloff, Karen L. ;

Gay, Cynthia L. ;

Anez, German ;

Adelglass, Jeffrey M. ;

Barrat Hernandez, Alejandro Q. ;

Harper, Wayne L. ;

Duncanson, Daniel M. ;

McArthur, Monica A. ;

Florescu, Diana F. ;

McClelland, R. Scott ;

Garcia-Fragoso, Veronica ;

Riesenberg, Robert A. ;

Musante, David B. ;

Fried, David L. ;

Safirstein, Beth E. ;

McKenzie, Mark ;

Jeanfreau, Robert J. ;

Kingsley, Jeffrey K. ;

Henderson, Jeffrey A. ;

Lane, Dakotah C. ;

Ruiz-Palacios, Guillermo M. ;

Corey, Lawrence ;

Neuzil, Kathleen M. ;

Coombs, Robert W. ;

Greninger, Alex L. ;

Hutter, Julia ;

Ake, Julie A. ;

Smith, Katherine ;

Woo, Wayne ;

Cho, Iksung ;

Glenn, Gregory M. ;

Dubovsky, Filip .

NEW ENGLAND JOURNAL OF MEDICINE, 2022, 386 (06) :531-543

[6] Immunogenicity, efficacy, and safety of CoronaVac and Pfizer/BioNTech mRNA vaccines in patients with psoriasis receiving systemic therapies: A prospective cohort study [J].

Ergun, Tulin ;

Tekin, Selcen Hosgoren ;

Sengun, Ozlem Apti ;

Cakici, Ozlem Akin ;

Seckin, Dilek ;

Adiay, Cumhur ;

Enul, Hakan ;

Yilmaz, Seval ;

Ay, Pinar ;

Haklar, Goncagul ;

Sili, Uluhan .

VACCINE, 2023, 41 (29) :4287-4294

[7]

Fabrizio M., 2022, Clin. Exp. Dermatol, V47, P2026

[8] 2019 update of EULAR recommendations for vaccination in adult patients with autoimmune inflammatory rheumatic diseases [J].

Furer, Victoria ;

Rondaan, Christien ;

Heijstek, Marloes W. ;

Agmon-Levin, Nancy ;

van Assen, Sander ;

Bijl, Marc ;

Breedveld, Ferry C. ;

D'Amelio, Raffaele ;

Dougados, Maxime ;

Kapetanovic, Meliha Crnkic ;

van Laar, Jacob M. ;

de Thurah, A. ;

Landewe, Robert B. M. ;

Molto, Anna ;

Mueller-Ladner, Ulf ;

Schreiber, Karen ;

Smolar, Leo ;

Walker, Jim ;

Warnatz, Klaus ;

Wulffraat, Nico M. ;

Elkayam, Ori .

ANNALS OF THE RHEUMATIC DISEASES, 2020, 79 (01) :39-52

[9] Alopecia areata after COVID-19 vaccination [J].

Gallo, Giuseppe ;

Mastorino, Luca ;

Tonella, Luca ;

Ribero, Simone ;

Guaglino, Pietro .

CLINICAL AND EXPERIMENTAL VACCINE RESEARCH, 2022, 11 (01) :129-132

[10] T-cell exhaustion in immune-mediated inflammatory diseases: New implications for immunotherapy [J].

Gao, Zhanyan ;

Feng, Yang ;

Xu, Jinhua ;

Liang, Jun .

FRONTIERS IN IMMUNOLOGY, 2022, 13

← 1 2 3 4 5 6 →