BMI1 Inhibition Improves Lesion Burden in Cerebral Cavernous Malformations

被引：1

作者：

Valentino, Mariaelena ^{[1
]}

Malinverno, Matteo ^{[1
]}

Maderna, Claudio ^{[1
]}

Pham, Van-Cuong ^{[2
]}

Roedel, Claudia Jasmin ^{[2
]}

Zanardi, Federica ^{[1
]}

Arce, Maximiliano ^{[3
]}

Drufuca, Lorenzo ^{[4
]}

Rossetti, Grazisa ^{[1
]}

Magnusson, Peetra U. ^{[3
]}

Lampugnani, Maria Grazia ^{[1
]}

Dejana, Elisabetta ^{[1
]}

Abdelilah-Seyfried, Salim ^{[2
]}

Pagani, Massimiliano ^{[1
,4
]}

机构：

[1] AIRC Inst Mol Oncol, IFOM ETS, I-20139 Milan, Italy

[2] Potsdam Univ, Inst Biochem & Biol, Potsdam, Germany

[3] Uppsala Univ, Dept Immunol Genet & Pathol, Uppsala, Sweden

[4] Univ Milan, Dept Med Biotechnol & Translat Med, Milan, Italy

来源：

CIRCULATION | 2024年 / 150卷 / 09期

基金：

欧洲研究理事会; 瑞典研究理事会;

关键词：

cerebral cavernous malformations; endothelium drug therapy; polycomb repressive complexes;

D O I：

10.1161/CIRCULATIONAHA.123.067438

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：738 / 741

页数：4

共 16 条

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Lanfranconi, Silvia
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BMC NEUROLOGY, 2014, 14
[3] A novel CCM1mutation associated with multiple cerebral and vertebral cavernous malformations
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Dario Ronchi
Naghia Ahmed
Vittorio Civelli
Paola Basilico
Nereo Bresolin
Giacomo Pietro Comi
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BMC Neurology, 14
[4] ZPLD1 gene is disrupted in a patient with balanced translocation that exhibits cerebral cavernous malformations
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[5] Novel KRIT1 Mutation and No Molecular Evidence of Anticipation in a Family with Cerebral and Spinal Cavernous Malformations
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[7] Spectrum and expression analysis of KRIT1 mutations in 121 consecutive and unrelated patients with Cerebral Cavernous Malformations
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Christian Denier
Pierre Labauge
Michaelle Cécillon
Jacqueline Maciazek
Anne Joutel
Sophie Laberge-le Couteulx
Elisabeth Tournier-Lasserve
European Journal of Human Genetics, 2002, 10 : 733 - 740
[8] Spectrum and expression analysis of KRIT1 mutations in 121 consecutive and unrelated patients with Cerebral Cavernous Malformations
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Maciazek, J
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EUROPEAN JOURNAL OF HUMAN GENETICS, 2002, 10 (11) : 733 - 740
[9] Lectin-type oxidized LDL receptor-1 as a potential therapeutic target for cerebral cavernous malformations treatment
Ashok, Karthik
Martinez, Tyra
Sesen, Julie
Nasim, Sana
Lang, Shih-Shan
Heuer, Gregory
Tucker, Alexander
Lopez-Ramirez, Miguel Alejandro
Smith, Edward R.
Ghalali, Aram
FRONTIERS IN NEUROSCIENCE, 2024, 18
[10] Exome capture sequencing identifies a novel CCM1 mutation in a Chinese family with multiple cerebral cavernous malformations
Mao, Cheng-yuan
Yang, Jing
Zhang, Shu-yu
Luo, Hai-yang
Song, Bo
Liu, Yu-tao
Wu, Jun
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Yang, Zhi-hua
Du, Pan
Wang, Yao-he
Shi, Chang-he
Xu, Yu-ming
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