Severe Autoimmune Hemolytic Anemia Following Pneumococcal Vaccination in an Infant With Underlying Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency: Report of a Case and Review of the Literature

被引:0
作者
Panagopoulos, Panagiotis [1 ]
Kapetaniou, Konstantina [1 ]
Gkentzi, Despoina [2 ]
Biliris, Christos Dionysios [2 ]
Siomou, Ekaterini [1 ]
Makis, Alexandros [1 ]
机构
[1] Univ Ioannina, Univ Hosp Ioannina, Fac Med, Sch Hlth Sci, Ioannina, Greece
[2] Univ Hosp Patras, Dept Pediat, Patras, Greece
关键词
urinary tract infection; e coli; escherichia coli; vaccination; glucose-6-phosphate dehydrogenase deficiency; autoimmune hemolytic anemia; PATIENT;
D O I
10.7759/cureus.68552
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Autoimmune hemolytic anemia (AIHA) and glucose-6-phosphate dehydrogenase (G6PD) deficiency are two distinct causes of hemolysis in children and a combination of both diseases is considered rare, especially in early infancy. We present such a rare case of severe AIHA in an infant with G6PD deficiency in the setting of Escherichia coli urinary tract infection and recent pneumococcal vaccination history, with the goal of analyzing potential links between them, examining the causative role of vaccines, and reviewing available literature.
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