While policy termination is usually more difficult than continuity in domestic policymaking, the international process for addressing antimicrobial resistance (AMR) shows that sustaining commitments can be the more difficult path. Addressing persistent crises requires persistent policy responses across multiple countries. Policy coordination among many countries has gained significant scholarly attention whereas analyses of continuing, longer-term commitments of many countries to crisis response are less common. This paper remedies this shortfall by analysing the commitments of different countries to the international policy process against AMR. It triangulates novel evidence in the form of distinct indicators based on global surveys, content analysis of national action plans (NAPs), and publication patterns of second-generation NAPs. The findings suggest that national commitments to the international process initially reached high levels but are now in decline. Countries are effectively 'sunsetting' their NAPs, and thereby ending commitments to the international process for addressing AMR. Many have refrained from renewing their NAPs, and those that do renew rarely show signs of learning or adaptation from previous NAPs. Hence, even in the AMR case, where a global and persistent threat rose high on the international political agenda, long-term commitment to the international response policy process is by no means assured.