Laminar organization of visual responses in core and parabelt auditory cortex

被引:0
作者
Mackey, Chase A. [1 ]
O'Connell, Monica N. [1 ,2 ]
Hackett, Troy A. [3 ]
Schroeder, Charles E. [1 ,4 ,5 ]
Kajikawa, Yoshinao [1 ,2 ]
机构
[1] Nathan S Kline Inst Psychiat Res, Ctr Biomed Imaging & Neuromodulat, 140 Old Orangeburg Rd, Orangeburg, NY 10962 USA
[2] NYU, Sch Med, Dept Psychiat, 145 E 32nd St, New York, NY 10016 USA
[3] Vanderbilt Univ, Med Ctr, Dept Hearing & Speech Sci, 1211 Med Ctr Dr, Nashville, TN 37212 USA
[4] Columbia Univ, Coll Phys, Dept Psychiat, 630 W 168th St, New York, NY 10032 USA
[5] Columbia Univ, Coll Phys, Dept Neurol, 630 W 168th St, New York, NY 10032 USA
基金
美国国家卫生研究院;
关键词
audiovisual; multisensory; nonhuman primate; vocalization; rhesus macaque; SUPERIOR TEMPORAL REGION; MULTISENSORY INTERACTIONS; THALAMOCORTICAL CONNECTIONS; NEURONAL OSCILLATIONS; CORTICAL CONNECTIONS; POSTERIOR COMPLEX; FIELD POTENTIALS; MACAQUE MONKEY; DYNAMIC FACES; INFORMATION;
D O I
10.1093/cercor/bhae373
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Audiovisual (AV) interaction has been shown in many studies of auditory cortex. However, the underlying processes and circuits are unclear because few studies have used methods that delineate the timing and laminar distribution of net excitatory and inhibitory processes within areas, much less across cortical levels. This study examined laminar profiles of neuronal activity in auditory core (AC) and parabelt (PB) cortices recorded from macaques during active discrimination of conspecific faces and vocalizations. We found modulation of multi-unit activity (MUA) in response to isolated visual stimulation, characterized by a brief deep MUA spike, putatively in white matter, followed by mid-layer MUA suppression in core auditory cortex; the later suppressive event had clear current source density concomitants, while the earlier MUA spike did not. We observed a similar facilitation-suppression sequence in the PB, with later onset latency. In combined AV stimulation, there was moderate reduction of responses to sound during the visual-evoked MUA suppression interval in both AC and PB. These data suggest a common sequence of afferent spikes, followed by synaptic inhibition; however, differences in timing and laminar location may reflect distinct visual projections to AC and PB.
引用
收藏
页数:18
相关论文
empty
未找到相关数据