Prevalence of Co-Infections in Primary Care Patients with Medically Attended Acute Respiratory Infection in the 2022/2023 Season

被引:0
作者
Socan, Maja [1 ]
Prosenc, Katarina [2 ]
Mrzel, Maja [1 ]
机构
[1] Natl Inst Publ Hlth, Ljubljana 1000, Slovenia
[2] Natl Lab Hlth Environm & Food, Ljubljana 1000, Slovenia
来源
VIRUSES-BASEL | 2024年 / 16卷 / 08期
关键词
respiratory viruses; co-infections; acute respiratory infections; primary care; sentinel; influenza; SARS-CoV-2; RSV; CHILDREN; VIRUS;
D O I
10.3390/v16081289
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In the post-pandemic period, an endemic circulation of respiratory viruses has been re-established. Respiratory viruses are co-circulating with SARS-CoV-2. We performed a retrospective analysis of co-infections in primary care patients with medically attended acute respiratory infections (MAARI) who consulted from week 40/2022 to week 39/2023 and were tested for a panel of respiratory viruses. Out of 2099 samples tested, 1260 (60.0%) were positive for one virus. In 340 samples, co-infection was detected: two viruses in 281 (13.4%), three viruses in 51 (2.4%), and four viruses in eight (0.4%) samples. Respiratory viruses co-infected the patients with MAARI at very different rates. The lowest rates of co-infections were confirmed for influenza B (13.8%) and influenza A (22.9%) and the highest for human bocaviruses (84.0%) and human parechoviruses (82.1%). Co-infections were detected in 28.2% of SARS-CoV-2 positive samples. SARS-CoV-2 has never been co-infected with influenza B virus, enterovirus or adenovirus, although the latter was found as a co-infecting virus with all other respiratory viruses tested. The rate of co-infections decreased significantly with increasing age (p-value 0.000), and no difference was found regarding gender (p-value 0.672). It is important to understand the epidemiology of respiratory co-infections for prevention and management decisions in patients with MAARI.
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页数:10
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