The crystal structure of (Z)-3′-(2-(1-(3,4-dimethyl-phenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2′-hydroxy-[1,1′-biphenyl]-3-carboxylicacid - methanol (1/1), C26H26N4O5

被引:1
作者
Guo, Xiao [2 ]
Li, Tiejun [2 ]
Cao, Xueli [1 ]
Zhang, Wenhao [2 ]
机构
[1] Coll Taishan, Dept Chem & Chem Engn, Tai An 271000, Peoples R China
[2] Jewim Pharmaceut Shandong Co Ltd, Tai An 271000, Peoples R China
来源
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES | 2024年 / 239卷 / 05期
关键词
ELTROMBOPAG;
D O I
10.1515/ncrs-2024-0251
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
C26H26N4O5, triclinic, P (1) over bar (no. 2), a = 7.245(2) angstrom, b = 12.522(3) angstrom, c = 13.789(3) angstrom, alpha = 75.420(1)degrees, beta = 79.628(1)degrees, gamma = 83.226(1)degrees, V = 1,187.5(5) angstrom(3), Z = 2, R-gt(F) = 0.0467, wR(ref)(F-2) = 0.1399, T = 298 K.
引用
收藏
页码:957 / 959
页数:3
相关论文
共 12 条
[1]  
Brandenburg K., 2015, Diamond. Visual Crystal Structure Information System. Ver. 4.0
[2]  
Bruker, 2016, SAINT APEX2 SADABS
[3]   Eltrombopag in Aplastic Anemia [J].
Desmond, Ronan ;
Townsley, Danielle M. ;
Dunbar, Cynthia ;
Young, Neal S. .
SEMINARS IN HEMATOLOGY, 2015, 52 (01) :31-37
[4]   Eltrombopag in Immune Thrombocytopenia, Aplastic Anemia, and Myelodysplastic Syndrome: From Megakaryopoiesis to Immunomodulation [J].
Fattizzo, Bruno ;
Levati, Giorgia ;
Cassin, Ramona ;
Barcellini, Wilma .
DRUGS, 2019, 79 (12) :1305-1319
[5]   Crystal structure of 3,3′-dimethoxy-4,4′-oxy-di-benzaldehyde, C16H14O5 [J].
Huang, Shiyin ;
Yin, Minlei ;
Lin, Yuxin ;
Yang, Heyi ;
Chen, Jie ;
Qiu, Ting .
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES, 2024, 239 (04) :611-612
[6]   PubChem in 2021: new data content and improved web interfaces [J].
Kim, Sunghwan ;
Chen, Jie ;
Cheng, Tiejun ;
Gindulyte, Asta ;
He, Jia ;
He, Siqian ;
Li, Qingliang ;
Shoemaker, Benjamin A. ;
Thiessen, Paul A. ;
Yu, Bo ;
Zaslavsky, Leonid ;
Zhang, Jian ;
Bolton, Evan E. .
NUCLEIC ACIDS RESEARCH, 2021, 49 (D1) :D1388-D1395
[7]   Eltrombopag for use in children with immune thrombocytopenia [J].
Kim, Taylor Olmsted ;
Despotovic, Jenny ;
Lambert, Michele P. .
BLOOD ADVANCES, 2018, 2 (04) :454-461
[8]   Coordination Compounds of Bivalent Metals with (Z)-4-(2-Hydroxy-5-nitrophenyl)hydrazono-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one: Crystal and Molecular Structure of C16H13N5O4 [J].
Koval'chukova, O. V. ;
Strashnova, S. B. ;
Avramenko, O. V. ;
Ryabov, M. A. ;
Dorovatovskii, P. V. ;
Zubavichus, Ya. V. ;
Khrustalev, V. N. .
RUSSIAN JOURNAL OF INORGANIC CHEMISTRY, 2018, 63 (07) :874-880
[9]   Prolonged use of eltrombopag in patients with severe aplastic anemia in the real world [J].
Li, Ruixin ;
Wang, Ningling ;
Chai, Xingxing ;
Yang, Linhai ;
Liu, Kangkang ;
He, Hailong ;
Lin, Shengyun ;
Yang, Yan ;
Jia, Jinsong ;
Zhang, Donghua ;
Gong, Yuemin ;
Shi, Jinning ;
He, Guangsheng ;
Li, Jianyong .
CLINICAL AND EXPERIMENTAL MEDICINE, 2023, 23 (06) :2619-2627
[10]   Hydrazone to deprotonated azo/azo-enol transformation for isomeric pyrazolone based heterocyclic dyes via metal-ion complexation [J].
Qian, Hui-Fen ;
Geng, Jiao ;
Xu, Dan ;
Huang, Wei .
DYES AND PIGMENTS, 2019, 160 :853-862