DNA origami force probes illuminate T cell receptor forces at the immune synapse

被引：0

作者：

Le, Tram Thi Hong ^{[1
]}

Kim, Byoung Choul ^{[1
]}

机构：

[1] Incheon Natl Univ, Dept Nanobioengn, Incheon, South Korea

来源：

NATURE NANOTECHNOLOGY | 2024年 / 19卷 / 11期

关键词：

D O I：

10.1038/s41565-024-01768-1

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

DNA origami tension sensors, created by integrating DNA origami sheets with molecular tension probes, enable the quantification of mechanical forces involved in T cell receptor interactions at intermembrane junctions.

引用

页码：1583 / 1584

页数：2

共 7 条

[1] Mechanosensing drives acuity of αβ T-cell recognition
Feng, Yinnian
Brazin, Kristine N.
Kobayashi, Eiji
Mallis, Robert J.
Reinherz, Ellis L.
Lang, Matthew J.
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 114 (39) : E8204 - E8213
[2] Quantifying T cell receptor mechanics at membrane junctions using DNA origami tension sensors
Hu, Yuesong
Rogers, Jhordan
Duan, Yuxin
Velusamy, Arventh
Narum, Steven
Al Abdullatif, Sarah
Salaita, Khalid
[J]. NATURE NANOTECHNOLOGY, 2024, 19 (11) : 1674 - 1685
[3] Accumulation of Dynamic Catch Bonds between TCR and Agonist Peptide-MHC Triggers T Cell Signaling
Liu, Baoyu
Chen, Wei
Evavold, Brian D.
Zhu, Cheng
[J]. CELL, 2014, 157 (02) : 357 - 368
[4] Malinouski M, 2014, NAT COMMUN, V5, DOI [10.1038/ncomms4301, 10.1038/ncomms6167]
[5] Folding DNA to create nanoscale shapes and patterns
Rothemund, PWK
[J]. NATURE, 2006, 440 (7082) : 297 - 302
[6] How TCRs bind MHCs, peptides, and coreceptors
Rudolph, Markus G.
Stanfield, Robyn L.
Wilson, Ian A.
[J]. ANNUAL REVIEW OF IMMUNOLOGY, 2006, 24 : 419 - 466
[7] Design and self-assembly of two-dimensional DNA crystals
Winfree, E
Liu, FR
Wenzler, LA
Seeman, NC
[J]. NATURE, 1998, 394 (6693) : 539 - 544

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