Research progress of surface-active ionic liquids for drug delivery

被引：8
|
作者：
Zhen, Dawei [1 ]
Zhang, Miaomiao [1 ]
Liu, Fengmao [1 ]
Peng, Qingrong [1 ]
机构：
[1] China Agr Univ, Coll Sci, Beijing 100193, Peoples R China
来源：
JOURNAL OF MOLECULAR LIQUIDS | 2024年 / 400卷
关键词：
Surface activity; Ionic liquids; Self-assembly; Drug delivery; Theoretical calculation; MIXED MICELLIZATION; AMITRIPTYLINE HYDROCHLORIDE; PROPRANOLOL HYDROCHLORIDE; AGGREGATION BEHAVIOR; CATIONIC SURFACTANT; MICELLES; MIXTURES; TOXICITY; VESICLES; CHLORIDE;
D O I：
10.1016/j.molliq.2024.124546
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Surface-active ionic liquids (SAILs) are the category of ionic liquids specifically with long hydrophobic alkyl chains. Besides as an eco-friendly alternative to organic solvent, a multitude of reports have focused on the performance of SAILs that target at the drug-delivery application. This review introduces the typical structures, theoretical and experimental characterization techniques, aspects of safety, and self-assembly behaviors and interactions of SAILs for drug-delivery application. In particular, a total of 38 drugs reported with a SAIL research were summarized and discussed according to their hydrophilic, hydrophobic, and amphipathic natures.
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页数：13
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