To the Brain and Beyond: Neurological Implications of Glucagon-Like Peptide-1 Receptor Agonists

被引：1

作者：

Guevara, Lindsay R. Hunter ^{[1
]}

Beam, W. Brian B. ^{[1
]}

Pasternak, Jeffrey J. ^{[1
]}

机构：

[1] Mayo Clin, Coll Med, Dept Anesthesiol & Perioperat Med, Rochester, MN 55905 USA

来源：

JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY | 2024年 / 36卷 / 04期

关键词：

brain; diabetes mellitus; glucagon-like peptide-1 receptor agonists; neuroprotection; stroke; GLP-1; LIRAGLUTIDE;

D O I：

10.1097/ANA.0000000000000985

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have emerged as an increasingly popular class of medications commonly used for glycemic control in patients with type 2 diabetes mellitus and for weight loss. GLP-1 RAs also have potential benefits in patients with various neurological diseases independent of their glucose-modulating effect. In this focused review, we explore animal and clinical evidence evaluating the impact of GLP-1 RAs in common neurological diseases. Our aim is to provide a basis for hypothesis generation for future studies to assess the role that GLP-1 RAs may have on the nervous system, including implications for the perioperative period.

引用

页码：278 / 282

页数：5

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