Heart Failure in Rheumatoid Arthritis: Clinical Implications

被引：1

作者：

Zambrano Zambrano, Alexis ^{[1
]}

Del Rio Zanatta, Hector ^{[1
]}

Gonzalez Espinoza, Andrea ^{[2
]}

Bernal Alferes, Brian ^{[1
]}

Zambrano Zambrano, Kevin ^{[1
]}

Martinez Salazar, Julio ^{[1
]}

Ixcamparij Rosales, Carlos Haroldo ^{[3
]}

机构：

[1] Natl Med Ctr 20 Noviembre ISSSTEFelix Cuevas, Dept Internal Med, 540 Valle, Mexico City 03104, DF, Mexico

[2] Reg Hosp Lic Adolfo Lopez Mateos ISSSTE, Dept Ophthalmol, Mexico City, DF, Mexico

[3] Natl Med Ctr 20 Noviembre ISSSTE, Dept Echocardiog, Mexico City, DF, Mexico

来源：

CURRENT HEART FAILURE REPORTS | 2024年 / 21卷 / 06期

关键词：

Heart failure; Rheumatoid arthritis; Heart failure with preserved ejection fraction; Inflammation; C-reactive protein; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; NECROSIS-FACTOR-ALPHA; CARDIOVASCULAR-DISEASE; AMERICAN-COLLEGE; RISK-FACTORS; METHOTREXATE; INFLAMMATION; INHIBITORS; THERAPY; EVENTS;

D O I：

10.1007/s11897-024-00682-w

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Purpose of reviewThis review focuses on the association between RA and heart failure, highlighting the role of inflammation and the prevalence of heart failure with preserved ejection fraction (HFpEF) in this population.Recent findingsThe incidence of heart failure in RA patients is two to three times higher than in the general population, with inflammation playing a significant role independent of traditional cardiovascular risk factors. HFpEF accounts for about half of heart failure cases and is increasingly recognized in RA patients, although it remains underdiagnosed. Atypical presentations and non-specific symptoms further complicate diagnosis. Early control of inflammation has been shown to reduce the risk of heart failure development and progression, improving both morbidity and mortality outcomes.SummaryRheumatoid arthritis (RA) is a systemic inflammatory disease affecting approximately 1% of the population, with cardiovascular disease being the leading cause of premature death in these patients.

引用

页码：530 / 540

页数：11

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