Review on Hyaluronic Acid Functionalized Sulfur and Nitrogen Co-Doped Graphene Quantum Dots Nano Conjugates for Targeting of Specific Type of Cancer

被引:1
作者
Patil, Vinit Sudhakar [1 ]
Bavaskar, Kedar Rupa [2 ]
Morani, Dilip Omprakash [3 ,4 ]
Jain, Ashish Suresh [2 ]
机构
[1] Shri DD Vispute Coll Pharm & Res Ctr, New Panvel 410206, India
[2] Shri DD Vispute Coll Pharm & Res Ctr, Dept Pharmaceut, New Panvel 410206, India
[3] Shri DD Vispute Coll Pharm & Res Ctr, Dept Pharmacognosy, New Panvel 410206, India
[4] Bombay Inst Pharm & Res, Dept Pharmaceut, Dombivali 421204, India
关键词
Nanotechnology; Hyaluronic; acid; Graphene quantum; dots; Cancer; Nanoparticles; Fluorescence; Tumor; Drug; delivery; TUNABLE PHOTOLUMINESCENCE; INDUCED FLUORESCENCE; STEP SYNTHESIS; DRUG-DELIVERY; CURRENT STATE; NANOPARTICLES; OXIDE; STRATEGIES; THERAPY; SIZE;
D O I
10.34172/apb.2024.043
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Many people lose their lives to cancer each year. The prevalence of illnesses, metabolic disorders, high-risk infections, and other conditions has been greatly slowed down by expanding scientific research. Chemotherapy and radiation are still the initial lines of treatment for cancer patients, along with surgical removal of tumors. Modifications have been made in chemotherapy since medicines frequently have substantial systemic toxicity and poor pharmacokinetics and still do not reach the tumor site at effective concentrations. Chemotherapy may now be administered more safely and effectively thanks to nanotechnology. Nanotechnology-based graphene quantum dots (GQDs) are very applicable in breast cancer detection, as a drug delivery system, and in the treatment of breast cancer because of their physical and chemical properties, lower toxicity, small size, fluorescence, and effective drug delivery. This paper analyzes the GQDs as cutting-edge platforms for biotechnology and nanomedicine also its application in drug delivery in cancer. It shows that GQDs can be effectively conjugated with hyaluronic acid (HA) to achieve efficient and target-specific delivery.
引用
收藏
页码:266 / 277
页数:12
相关论文
共 128 条
  • [1] Target Delivery and Cell Imaging Using Hyaluronic Acid-Functionalized Graphene Quantum Dots
    Abdullah-Al-Nahain
    Lee, Jung-Eun
    In, Insik
    Lee, Haeshin
    Lee, Kang Dae
    Jeong, Ji Hoon
    Park, Sung Young
    [J]. MOLECULAR PHARMACEUTICS, 2013, 10 (10) : 3736 - 3744
  • [2] Alberts B., 2014, Essential Cell Biology, V4th, DOI DOI 10.1201/9781315815015
  • [3] Bioengineering Strategies for Designing Targeted Cancer Therapies
    Alexander-Bryant, Angela A.
    Vanden Berg-Foels, Wendy S.
    Wen, Xuejun
    [J]. ADVANCES IN CANCER RESEARCH, VOL 118, 2013, 118 : 1 - 59
  • [4] An overview of active and passive targeting strategies to improve the nanocarriers efficiency to tumour sites
    Attia, Mohamed F.
    Anton, Nicolas
    Wallyn, Justine
    Omran, Ziad
    Vandamme, Thierry F.
    [J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 2019, 71 (08) : 1185 - 1198
  • [5] Quantum dots as photosensitizers?
    Bakalova, R
    Ohba, H
    Zhelev, Z
    Ishikawa, M
    Baba, Y
    [J]. NATURE BIOTECHNOLOGY, 2004, 22 (11) : 1360 - 1361
  • [6] Multifunctional Nanocarriers for diagnostics, drug delivery and targeted treatment across blood-brain barrier: perspectives on tracking and neuroimaging
    Bhaskar, Sonu
    Tian, Furong
    Stoeger, Tobias
    Kreyling, Wolfgang
    de la Fuente, Jesus M.
    Grazu, Valeria
    Borm, Paul
    Estrada, Giovani
    Ntziachristos, Vasilis
    Razansky, Daniel
    [J]. PARTICLE AND FIBRE TOXICOLOGY, 2010, 7
  • [7] One-pot synthesis of sulfur-doped graphene quantum dots as a novel fluorescent probe for highly selective and sensitive detection of lead(II)
    Bian, Shiyue
    Shen, Chao
    Hua, Hong
    Zhou, Lin
    Zhu, Hailin
    Xi, Fengna
    Liu, Jiyang
    Dong, Xiaoping
    [J]. RSC ADVANCES, 2016, 6 (74): : 69977 - 69983
  • [8] Semiconductor nanocrystals as fluorescent biological labels
    Bruchez, M
    Moronne, M
    Gin, P
    Weiss, S
    Alivisatos, AP
    [J]. SCIENCE, 1998, 281 (5385) : 2013 - 2016
  • [9] Liquid-phase laser ablation synthesis of graphene quantum dots from carbon nano-onions: Comparison with chemical oxidation
    Calabro, Rosemary L.
    Yang, Dong-Sheng
    Kim, Doo Young
    [J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2018, 527 : 132 - 140
  • [10] A Perspective on Cancer Cell Metastasis
    Chaffer, Christine L.
    Weinberg, Robert A.
    [J]. SCIENCE, 2011, 331 (6024) : 1559 - 1564