A Complex Presentation: Psychosis in a Patient Diagnosed With Lennox-Gastaut Syndrome

被引:0
作者
Singh, Gurraj [1 ]
Gill, Gurtej [2 ]
Singh, Satwant [3 ]
Roshan, Nikhita S. [4 ]
Lalendran, Akshita [5 ]
Gunturu, Sasidhar [2 ]
机构
[1] Bergen New Bridge Med Ctr, Psychiat, Paramus, NJ 07652 USA
[2] BronxCare Hlth Syst, Psychiat, New York, NY USA
[3] Interfaith Med Ctr, Psychiat & Behav Sci, Brooklyn, NY USA
[4] Father Muller Med Coll, Neurol, Mangalore, India
[5] BronxMedcare Hosp, Psychiat & Behav Sci, New York, NY USA
关键词
breakthrough seizure; seizure activity; psychosis; childhood epilepsy; lennox-gastaut syndrome; DE-NOVO MUTATIONS; CACNA1A; EPILEPSY;
D O I
10.7759/cureus.65010
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Lennox-Gastaut syndrome (LGS) is a form of severe childhood epilepsy, with most children experiencing seizures before reaching the age of eight. Typically, patients have multiple types of seizures, making an accurate diagnosis challenging. While it can be secondary to other causes, often, it is idiopathic. Over time, children develop cognitive impairment, leading to intellectual disability. The mainstay of treatment and management is seizure control. However, management remains challenging due to the complexity of the syndrome, as it is associated with multiple seizure types, intellectual deterioration, and other psychiatric comorbidities. We present the case of a 19-year-old male diagnosed with LGS and treated with various available therapies, who demonstrated multiple breakthrough seizures, significant neurocognitive disabilities, and behavior challenges. Additionally, the patient displayed psychotic features of auditory hallucinations, aggression, and attempts at self-mutilation, a rare clinical presentation in LGS.
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页数:4
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