Efficacy of 1060 nm Diode Laser for Non-Invasive Subcutaneous Fat Reduction in Mini-Pigs

被引：0

作者：

Lee, Yea-Jin ^{[1
,2
]}

Hong, Namgue ^{[2
]}

Choi, Eun Seo ^{[3
]}

Choi, Sun-Hyang ^{[2
]}

Kim, Eun Young ^{[2
]}

Park, Hyeong Ju ^{[4
]}

Ahn, Jin-Chul ^{[1
,2
]}

机构：

[1] Dankook Univ, Dept Med, Cheonan Si 31116, South Korea

[2] Dankook Univ, Med Laser Res Ctr, Grad Sch Med, Cheonan Si 31116, South Korea

[3] Chosun Univ, Dept Phys, Gwangju 61452, South Korea

[4] Korea Photon Technol Inst, Bio&Hlth Photon Res Ctr, Gwangju 61007, South Korea

来源：

CLINICAL COSMETIC AND INVESTIGATIONAL DERMATOLOGY | 2024年 / 17卷

基金：

新加坡国家研究基金会;

关键词：

diode laser; fat; abdominal; non-invasive; preclinical; ASSISTED LIPOLYSIS; SAFETY; LIPOSUCTION; APPEARANCE;

D O I：

10.2147/CCID.S471367

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Purpose: To evaluate the efficacy and safety of abdominal fat reduction in mini-pigs, utilizing at 1060 nm diode laser with a wavelength of 1060 nm. Patients and Methods: The laser system non-invasively disrupts adipose tissue; its effectiveness and safety were evaluated by ultrasound imaging and histological analysis. Laser irradiation was performed with various powers, and the cooling function was activated to prevent skin surface damage. Results: The dermal tissue temperature increased to at least 43 degrees C during laser exposure, leading to a decrease in abdominal fat thickness after 30 days. Blood tests revealed no significant changes in kidney and liver function but showed increased blood levels of nonessential free acids (NEFAs), likely due to the release of fatty tissue-derived free fatty acids. Histological evaluation demonstrated rapid transformation of adipose tissue into collagen, muscle fibers, and intracellular fibrous tissue. Conclusion: The 1060 nm laser showed promise as a non-invasive and safe tool for reducing abdominal fat.

引用

页码：2097 / 2110

页数：14

共 26 条

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