共 28 条
Non-Faradaic Impedimetric Detection of Heavy Metal Ions via a Hybrid Nanoparticle-DNAzyme Biosensor
被引:0
作者:
Panagopoulou, Chrysi
[1
]
Skotadis, Evangelos
[1
,2
]
Aslanidis, Evangelos
[1
,3
]
Tzourmana, Georgia
[1
]
Rapesi, Annita
[1
]
Tsioustas, Charalampos
[1
]
Kainourgiaki, Maria
[1
]
Kleitsiotis, Georgios
[1
]
Tsekenis, George
[4
]
Tsoukalas, Dimitrios
[1
]
机构:
[1] Natl Tech Univ Athens, Dept Appl Phys, Athens 15780, Greece
[2] Univ West Attica, Dept Biomed Engn, Athens 12243, Greece
[3] Fdn Res & Technol Hellas FORTH, Inst Elect Struct & Laser IESL, Microelect Res Grp MRG, Iraklion 70013, Greece
[4] Biomed Res Fdn Acad Athens, Athens 11527, Greece
来源:
BIOSENSORS-BASEL
|
2024年
/
14卷
/
07期
关键词:
heavy metal;
biosensor;
non-faradaic;
impedance;
EIS;
DNAzymes;
chromium;
lead;
nanoparticles;
lab on chip;
DNA;
DROPLET;
MICROELECTRODES;
ENVIRONMENT;
REMOVAL;
D O I:
10.3390/bios14070321
中图分类号:
O65 [分析化学];
学科分类号:
070302 ;
081704 ;
摘要:
Due to rapid industrialization, novel water-quality monitoring techniques for the detection of highly toxic and hazardous heavy metal ions are essential. Herein, a hybrid noble nanoparticle/DNAzyme electrochemical biosensor is proposed for the simultaneous and label-free detection of Pb2+ and Cr3+ in aqueous solutions. The sensor is based on the combination of a two-dimensional naked-platinum nanoparticle film and DNAzymes, whose double-helix configuration disassembles into smaller fragments in the presence of target-specific heavy metal ions. The electrochemical behavior of the fabricated sensor was investigated with non-faradaic electrochemical impedance spectroscopy (EIS), resulting in the successful detection of Pb2+ and Cr3+ well below their maximum permitted levels in tap water. So far, there has been no report on the successful detection of heavy metal ions utilizing the non-faradaic electrochemical impedance spectroscopy technique based on advanced nanomaterials paired with DNAzymes. This is also one of the few reports on the successful detection of chromium (III) via a sensor incorporating DNAzymes.
引用
收藏
页数:21
相关论文
共 28 条