ETCTN 10366: A phase 1 study of DNA-PK inhibitor peposertib in combination with hypofractionated radiotherapy for the treatment of locally advanced pancreatic adenocarcinoma

被引:0
|
作者
Davis, S. Lindsey
Kasi, Anup
Dayyani, Farshid
Ocean, Allyson J.
Chung, Vincent
Al Hallak, Mohammed Najeeb
Fountzilas, Christos
Hu, Junxiao
Murray, Judy
Allegra, Carmen
Gore, Steven
Beumer, Jan Hendrik
Goodman, Karyn A.
机构
[1] Univ Colorado, Canc Ctr, Aurora, CO USA
[2] Univ Kansas, Canc Ctr, Westwood, KS USA
[3] Univ Calif Irvine, Chao Family Comprehens Canc Ctr, Orange, CA 92668 USA
[4] NewYork Presbyterian Weill Cornell Med Ctr, New York, NY USA
[5] City Hope Comprehens Canc Ctr, Duarte, CA USA
[6] Wayne State Univ, Karmanos Canc Inst, Detroit, MI USA
[7] Roswell Park Comprehens Canc Ctr, Buffalo, NY USA
[8] Johns Hopkins Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD USA
[9] NCI, Bethesda, MD 20892 USA
[10] UPMC Hillman Canc Ctr, Pittsburgh, PA USA
[11] Icahn Sch Med Mt Sinai, Dept Radiat Oncol, New York, NY 10029 USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
4168
引用
收藏
页数:1
相关论文
共 50 条
  • [21] First-In-Human Phase I Study Of A Dual mTOR Kinase And DNA-PK Inhibitor (CC-115) In Advanced Malignancy
    Munster, Pamela
    Mita, Monica
    Mahipal, Amit
    Nemunaitis, John
    Massard, Christophe
    Mikkelsen, Tom
    Cruz, Cristina
    Paz-Ares, Luis
    Hidalgo, Manuel
    Rathkopf, Dana
    Blumenschein, George, Jr.
    Smith, David C.
    Eichhorst, Barbara
    Cloughesy, Tim
    Filvaroff, Ellen H.
    Li, Shaoyi
    Raymon, Heather
    de Haan, Hans
    Hege, Kristen
    Bendell, Johanna C.
    CANCER MANAGEMENT AND RESEARCH, 2019, 11 : 10463 - 10476
  • [22] A phase I dose escalation study of eryaspase in combination with modified FOLFIRINOX in locally advanced and metastatic pancreatic ductal adenocarcinoma
    Yin, Chao
    Marshall, John
    Macke, Laura Ann
    He, Aiwu Ruth
    Bouker, Kerrie
    Weinberg, Benjamin Adam
    Mukherji, Reetu
    Weiner, Louis M.
    Wang, Hongkun
    Geng, Xue
    Hoke, Frank
    Youssoufian, Hagop
    El-Hariry, Iman
    Noel, Marcus Smith
    JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (16)
  • [23] Phase I Dose-Finding Study of Vandetanib in Combination with Gemcitabine in Locally Advanced Unresectable or Metastatic Pancreatic Adenocarcinoma
    Saletti, Piercarlo
    Sessa, Cristiana
    De Dosso, Sara
    Cerny, Thomas
    Renggli, Verena
    Koeberle, Dieter
    ONCOLOGY, 2011, 81 (01) : 50 - 54
  • [24] A Phase 1 Study of Gemcitabine and S-1 Concurrent Radiotherapy in Patients With Locally Advanced Pancreatic Cancer
    Matsumura, Yuji
    Suyama, Masafumi
    Sai, Jinkan
    Kubokawa, Yoshihiro
    Kamiya, Takayoshi
    Watanabe, Sumio
    PANCREAS, 2011, 40 (05) : 799 - 800
  • [25] A phase 1 study of gemcitabine/nab-paclitaxel/S-1 (GAS) combination neoadjuvant chemotherapy for patients with locally advanced pancreatic adenocarcinoma
    Naru Kondo
    Yoshiaki Murakami
    Kenichiro Uemura
    Takeshi Sudo
    Yasushi Hashimoto
    Naoya Nakagawa
    Shinya Takahashi
    Hiroki Ohge
    Taijiro Sueda
    Cancer Chemotherapy and Pharmacology, 2017, 79 : 775 - 781
  • [26] A phase 1 study of gemcitabine/nab-paclitaxel/S-1 (GAS) combination neoadjuvant chemotherapy for patients with locally advanced pancreatic adenocarcinoma
    Kondo, Naru
    Murakami, Yoshiaki
    Uemura, Kenichiro
    Sudo, Takeshi
    Hashimoto, Yasushi
    Nakagawa, Naoya
    Takahashi, Shinya
    Ohge, Hiroki
    Sueda, Taijiro
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2017, 79 (04) : 775 - 781
  • [27] Combination of modified FOLFIRINOX with stereotactic body radiotherapy as an induction therapy for locally advanced pancreatic adenocarcinoma - a prospective single-arm study
    Piatek, Micha
    Bienkowski, Micha
    Kusnierz, Katarzyna
    Pilch-Kowalczyk, Joanna
    Imielska-Zdunek, Dorota
    Mrowiec, Sawomir
    Lampe, Pawe
    Radecka, Barbara
    Nawrocki, Sergiusz
    WSPOLCZESNA ONKOLOGIA-CONTEMPORARY ONCOLOGY, 2024, 28 (01): : 15 - 30
  • [28] A phase 1b trial of concurrent immunotherapy and irreversible electroporation in the treatment of locally advanced pancreatic adenocarcinoma
    O'Neill, Conor
    Hayat, Traci
    Hamm, John
    Healey, Mary
    Zheng, Qianqian
    Li, Yan
    Martin, Robert C. G., II
    SURGERY, 2020, 168 (04) : 610 - 616
  • [29] A phase I study of hypofractionated radiotherapy followed by systemic chemotherapy of full-dose Gemcitabine in patients with unresectable locally advanced pancreatic carcinoma
    Furuse, Junji
    Ishii, Hiroshi
    Kawashima, Mitsuhiko
    Nagase, Michitaka
    Ogino, Takashi
    Yoshino, Masahiro
    ANNALS OF ONCOLOGY, 2004, 15 : 242 - 242
  • [30] A phase I study of hypofractionated radiotherapy followed by systemic chemotherapy with full-dose gemcitabine in patients with unresectable locally advanced pancreatic cancer
    Furuse, Junji
    Ishii, Hiroshi
    Kawashima, Mitsuhiko
    Nagase, Michitaka
    Nihei, Keiji
    Nakachi, Kohei
    Ogino, Takashi
    Yoshino, Masahiro
    HEPATO-GASTROENTEROLOGY, 2007, 54 (77) : 1575 - 1578