In Pursuit of an Opioid-Free Pediatric Ambulatory Surgery Center: A Quality Improvement Initiative

被引:36
作者
Franz, Amber M. [1 ]
Martin, Lynn D. [1 ]
Liston, David E. [1 ]
Latham, Gregory J. [1 ]
Richards, Michael J. [1 ]
Low, Daniel K. [1 ]
机构
[1] Univ Washington, Dept Anesthesiol & Pain Med, Seattle Childrens, MB 11-500, Seattle, WA 98105 USA
关键词
STATISTICAL PROCESS-CONTROL; DOSE DEXMEDETOMIDINE; INDUCED HYPERALGESIA; DOUBLE-BLIND; PAIN; RECOVERY; IMPACT;
D O I
10.1213/ANE.0000000000004774
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
BACKGROUND: Opioids have been a central component of routine adult and pediatric anesthesia for decades. However, the long-term effects of perioperative opioids are concerning. Recent studies show a 4.8%-6.5% incidence of persistent opioid use after surgery in older children and adults. This means that >2 million of the 50 million patients undergoing elective surgeries in the United States each year are likely to develop persistent opioid use. With this in mind, anesthesiologists at Bellevue Clinic and Surgery Center assembled an interdisciplinary quality improvement team focused on 2 goals: (1) develop effective anesthesia protocols that minimize perioperative opioids and (2) add value to clinical services by maintaining or improving perioperative outcomes while reducing costs. This article describes our project and findings but does not attempt to make inferences or generalizations about populations outside our facility. METHODS: We performed a large-scale implementation of opioid-sparing protocols at our standalone pediatric clinic and ambulatory surgery facility, based in part on the prior success of our previously published tonsillectomy and adenoidectomy protocol. Multiple Plan-Do-Study-Act cycles were performed using data captured from the electronic medical record. The percentage of surgical patients receiving intraoperative opioids and postoperative morphine preintervention and postintervention were compared. The following measures were evaluated using statistical process control charts: maximum postoperative pain score, postoperative morphine rescue rate, total postanesthesia care unit minutes, total anesthesia minutes, and postoperative nausea and vomiting rescue rate. Intraoperative analgesic costs were calculated. RESULTS: Between January 2017 and June 2019, 10,948 surgeries were performed at Bellevue, with 10,733 cases included in the analyses. Between December 2017 and June 2019, intraoperative opioid administration at our institution decreased from 84% to 8%, and postoperative morphine administration declined from 11% to 6% using analgesics such as dexmedetomidine, nonsteroidal anti-inflammatory drugs, and regional anesthesia. Postoperative nausea and vomiting rescue rate decreased, while maximum postoperative pain scores, total anesthesia minutes, and total postanesthesia care unit minutes remained stable per control chart analyses. Costs improved. CONCLUSIONS: By utilizing dexmedetomidine, nonsteroidal anti-inflammatory drugs, and regional anesthesia for pediatric ambulatory surgeries at our facility, perioperative opioids were minimized without compromising patient outcomes or value.
引用
收藏
页码:788 / 797
页数:10
相关论文
共 36 条
  • [1] THE POSTANESTHESIA RECOVERY SCORE REVISITED
    ALDRETE, JA
    [J]. JOURNAL OF CLINICAL ANESTHESIA, 1995, 7 (01) : 89 - 91
  • [2] Short-term infusion of the μ-opioid agonist remifentanil in humans causes hyperalgesia during withdrawal
    Angst, MS
    Koppert, W
    Pahl, I
    Clark, DJ
    Schmelz, M
    [J]. PAIN, 2003, 106 (1-2) : 49 - 57
  • [3] Effect of Perioperative Systemic α2 Agonists on Postoperative Morphine Consumption and Pain Intensity Systematic Review and Meta-analysis of Randomized Controlled Trials
    Blaudszun, Gregoire
    Lysakowski, Christopher
    Elia, Nadia
    Tramer, Martin R.
    [J]. ANESTHESIOLOGY, 2012, 116 (06) : 1312 - 1322
  • [4] Parenteral Opioid Shortage - Treating Pain during the Opioid-Overdose Epidemic
    Bruera, Eduardo
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2018, 379 (07) : 601 - 603
  • [5] New Persistent Opioid Use After Minor and Major Surgical Procedures in US Adults
    Brummett, Chad M.
    Waljee, Jennifer F.
    Goesling, Jenna
    Moser, Stephanie
    Lin, Paul
    Englesbe, Michael J.
    Bohnert, Amy S. B.
    Kheterpal, Sachin
    Nallamothu, Brahmajee K.
    [J]. JAMA SURGERY, 2017, 152 (06)
  • [6] CDC, 2019, FASTSTATS
  • [7] Center for Disease Control, 2019, DRUG OVERDOSE DEATHS
  • [8] Intraoperative high dose fentanyl induces postoperative fentanyl tolerance
    Chia, YT
    Liu, K
    Wang, JJ
    Kuo, MC
    Ho, ST
    [J]. CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE, 1999, 46 (09): : 872 - 877
  • [9] Dexter F, 2019, Periop Care Oper Room Manag, V16, DOI [10.1016/j.pcorm.2019.100076, DOI 10.1016/J.PCORM.2019.100076]
  • [10] Opioid-induced hyperalgesia in patients after surgery: a systematic review and a meta-analysis
    Fletcher, D.
    Martinez, V.
    [J]. BRITISH JOURNAL OF ANAESTHESIA, 2014, 112 (06) : 991 - 1004