A brisk peripheral T-cell reaction following rituximab treatment for follicular lymphoma

被引：0
作者：
Frusteri, Cristina [1 ]
Ferrarini, Isacco [1 ]
机构：
[1] Univ Verona, Dept Engn Innovat Med, Canc Res & Cell Biol Lab, Verona, Italy
来源：
ANNALS OF HEMATOLOGY | 2024年
关键词：
Follicular lymphoma; Rituximab; T cells; Lymphocytosis; ANTIBODY; THERAPY;
D O I：
10.1007/s00277-024-05931-5
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Bone marrow reactive T-cell infiltrates have been frequently observed in patients affected by follicular lymphoma after rituximab treatment. In some studies, bone-marrow T-cell expansion has been associated with an effective anti-tumor response and favorable prognosis. In this manuscript, we report on a particularly brisk CD4(+) T-cell reaction occurring after rituximab treatment for follicular lymphoma and involving the peripheral blood in addition to the bone marrow. Peripheral blood T-cell reaction was mainly composed of effector-memory CD4(+) T cells and may reflect the expansion of an effective anti-tumor immunity.
引用
收藏
页码：6035 / 6037
页数：3
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