Synthesis and Pharmacological Activities of Benzothiazole Derivatives

The Research and Development in benzothiazole-based medicinal ingredients have turn into a hastily on the rise and gradually more lively topic. Broad number of compounds having Benzothiazole (BTZ) moiety are involved in the treatment of a various number of diseases with maximum curative potency. This review is aimed to afford modern progress in the synthesis of Benzothiazole analogues associated to the green chemistry. Literature surveys on scientific national and international journals, books as well as electronic resources were performed. Benzothiazole and its moieties containing various numbers of structural multiplicities play evidence in search of different pharmacological actions. This review steadily grants an all-inclusive review in the progressive developments of Benzothiazole-based compounds of medicinal chemistry as antibacterial, Hepatitis-C virus inhibitors, anti-alzheimer's disease, anti-inflammatory and analgesic, antioxidant, anti-convulsant, anti-diabetic, anti-histaminic, anti-malarial, anti-depressant and other medicinal agents. The wide field of pharmacological activity in creature benzothiazole derivative indicates that this string of compounds is of an unquestionable curiosity. This review is also believed to be extra efficient in finding pathogenic problems and diagnostic analogues is ready to find new-fangled judgment in the chase for drawing of a reduced amount of toxic and additional active Benzothiazole-based drugs. It is projected that this knowledge would give rise and show enormous impact for the growth of synthetic pathways for benzothiazoles with expansion of novel synthetic approaches.