The Effect of Protein Nutritional Support on Inflammatory Bowel Disease and Its Potential Mechanisms

被引:4
作者
Li, Qingye [1 ]
Wang, Jing [1 ]
机构
[1] Minist Agr & Rural Affairs, Inst Food & Nutr Dev, Beijing 100081, Peoples R China
关键词
protein nutritional support; inflammatory bowel disease; mechanisms of action; clinical application; IBD complications; NF-KAPPA-B; NECROSIS-FACTOR-ALPHA; CROHNS-DISEASE; INTESTINAL BARRIER; GUT MICROBIOTA; WHEY-PROTEIN; SOY PROTEIN; ULCERATIVE-COLITIS; GENE-EXPRESSION; BODY-COMPOSITION;
D O I
10.3390/nu16142302
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Inflammatory bowel disease (IBD), a complex chronic inflammatory bowel disorder that includes Crohn's disease (CD) and Ulcerative Colitis (UC), has become a globally increasing health concern. Nutrition, as an important factor influencing the occurrence and development of IBD, has attracted more and more attention. As the most important nutrient, protein can not only provide energy and nutrition required by patients, but also help repair damaged intestinal tissue, enhance immunity, and thus alleviate inflammation. Numerous studies have shown that protein nutritional support plays a significant role in the treatment and remission of IBD. This article presents a comprehensive review of the pathogenesis of IBD and analyzes and summarizes the potential mechanisms of protein nutritional support in IBD. Additionally, it provides an overview of the clinical effects of protein nutritional support in IBD and its impact on clinical complications. Research findings reveal that protein nutritional support demonstrates significant benefits in improving clinical symptoms, reducing the risk of complications, and improving quality of life in IBD patients. Therefore, protein nutritional support is expected to provide a new approach for the treatment of IBD.
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页数:26
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