Health-related quality of life and mental health in patients with major bone and joint infections

被引:2
作者
Wetzel, K. [1 ,2 ,3 ]
Clauss, M. [1 ,2 ,3 ]
Joeris, A. [4 ]
Kates, S. [5 ]
Morgenstern, M. [1 ,2 ,3 ]
机构
[1] Univ Hosp Basel, Ctr Musculoskeletal Infect, Basel, Switzerland
[2] Univ Hosp Basel, Dept Orthopaed & Trauma Surg, Basel, Switzerland
[3] Univ Basel, Basel, Switzerland
[4] AO Innovat Translat Ctr, Dubendorf, Switzerland
[5] Virginia Commonwealth Univ, Dept Orthopaed Surg, Richmond, VA USA
来源
BONE & JOINT OPEN | 2024年 / 5卷 / 09期
关键词
IMPLANT RETENTION; HIP; ANTIBIOTICS; DEBRIDEMENT; PERSISTENT; MORTALITY; RECURRENT; MOBILITY; IMPACT;
D O I
10.1302/2633-1462.59.BJO-2024-0072.R1
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Aims It is well described that patients with bone and joint infections (BJIs) commonly experience significant functional impairment and disability. Published literature is lacking on the impact of BJIs on mental health. Therefore, the aim of this study was to assess health-related quality of life (HRQoL) and the impact on mental health in patients with BJIs. Methods The AO Trauma Infection Registry is a prospective multinational registry. In total, 229 adult patients with long-bone BJI were enrolled between 1 November 2012 and 31 August 2017 in 18 centres from ten countries. Clinical outcome data, demographic data, and details on infections and treatments were collected. Patient-reported outcomes using the 36-Item Short-Form Health Survey questionnaire (SF-36), Parker Mobility Score, and Katz Index of Independence in Activities of Daily Living were assessed at one, six, and 12 months. The SF-36 mental component subscales were analyzed and correlated with infection characteristics and clinical outcome. Results The SF-36 physical component summary mean at baseline was 30.9 (95% CI 29.7 to 32.0). At one month, it was unchanged (30.5; 95% CI 29.5 to 31.5; p = 0.447); it had improved statistically significantly at six months (35.5; 95% CI 34.2 to 36.7; p < 0.001) and at 12 months (37.9; 95% CI 36.4 to 39.3; p < 0.001). The SF-36 mental component summary mean at baseline was 42.5 (95% CI 40.8 to 44.2). At one month, it was unchanged (43.1; 95% CI 41.4 to 44.8; p = 0.458); it had improved statistically significantly at six months (47.1; 95% CI 45.4 to 48.7; p < 0.001) and at 12 months (46.7; 95% CI 45.0 to 48.5; p < 0.001). All mental subscales had improved by the end of the study, but mental health status remained compromised in comparison with the average USA population. Conclusion BJIs considerably impact HRQoL, particularly mental health. Patients suffering from BJIs reported considerable limitations in their daily and social activities due to psychological problems. Impaired mental health may be explained by the chronic nature of BJIs, and therefore the mental wellbeing of these patients should be monitored closely.
引用
收藏
页码:721 / 728
页数:8
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