Feeding the Body Through the Skin: Ethosomes and Transethosomes as a New Topical Delivery System for Bioactive Compounds

被引:1
|
作者
Esposito, Elisabetta [1 ]
Pecorelli, Alessandra [2 ]
Ferrara, Francesca [1 ]
Lila, Mary Ann [3 ]
Valacchi, Giuseppe [2 ,4 ,5 ]
机构
[1] Univ Ferrara, Dept Chem Pharmaceut & Agr Sci, Ferrara, Italy
[2] Univ Ferrara, Dept Environm & Prevent Sci, Ferrara, Italy
[3] North Carolina State Univ, Dept Food Bioproc & Nutr Sci, Kannapolis, NC USA
[4] North Carolina State Univ, Dept Anim Sci, Kannapolis, NC 28081 USA
[5] Kyung Hee Univ, Dept Food & Nutr, Seoul, South Korea
关键词
skin; ethosome; transethosome; topical administration; transdermal delivery; inflammation; DRUG-DELIVERY; STEM-CELLS; NANOPARTICLES; PENETRATION; ANTIOXIDANT; VESICLES; OZONE; PHASE;
D O I
10.1146/annurev-food-072023-034528
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Because the feeding of our body through the oral route can be associated with many drawbacks due to the degradation of natural molecules during transit in the gastrointestinal tract, a transdermal delivery strategy, usually employed in the pharmaceutical field, can present an effective alternative for delivery of bioactives and nutrients from foods. In this review, the chance to feed the body with nutritive and bioactive molecules from food through transdermal administration is discussed. Various nanotechnological devices employed for topical and transdermal delivery of bioactive compounds are described. In addition, mechanisms underlying their potential use in the delivery of nutritive molecules, as well as their capability to efficaciously reach the dermis and promote systemic distribution, are detailed.
引用
收藏
页码:53 / 78
页数:26
相关论文
共 50 条
  • [1] Development, characterization, and skin delivery studies of related ultradeformable vesicles: transfersomes, ethosomes, and transethosomes
    Ascenso, Andreia
    Raposo, Sara
    Batista, Catia
    Cardoso, Pedro
    Mendes, Tiago
    Praca, Fabiola Garcia
    Lopes Badra Bentley, Maria Vitoria
    Simoes, Sandra
    INTERNATIONAL JOURNAL OF NANOMEDICINE, 2015, 10 : 5837 - 5851
  • [2] Optimization of ethosomes for topical thymoquinone delivery for the treatment of skin acne
    Kausar, Hina
    Mujeeb, Mohd
    Ahad, Abdul
    Moolakkadath, Thasleem
    Aqil, Mohd
    Ahmad, Adil
    Akhter, Md Habban
    JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2019, 49 : 177 - 187
  • [3] Ethosomes-based topical delivery system of antihistaminic drug for treatment of skin allergies
    Goindi, Shishu
    Dhatt, Bhavnita
    Kaur, Amanpreet
    JOURNAL OF MICROENCAPSULATION, 2014, 31 (07) : 716 - 724
  • [4] Nano-transethosomes: A Novel Tool for Drug Delivery through Skin
    Bajaj, Kajal Jagdish
    Parab, Bhagyashri Surendra
    Shidhaye, Supriya Shrihari
    INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH, 2021, 55 (01) : S1 - S10
  • [5] The skin delivery of tofacitinib citrate using transethosomes and hybridized ethosomes/nanostructured lipid carriers for vitiligo therapy: Dermatopharmacokinetics and in vivo assays
    Hesham, Heba
    Rady, Mai
    Hathout, Rania M.
    Abdel-Halim, Mohammad
    Mansour, Samar
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2022, 629
  • [6] Ethosomes: A novel delivery system for antifungal drugs in the treatment of topical fungal diseases
    Bhalaria, M. K.
    Naik, Sachin
    Misra, A. N.
    INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY, 2009, 47 (05) : 368 - 375
  • [7] Ethosomes of Phenylethyl Resorcinol as Vesicular Delivery System for Skin Lightening Applications
    Limsuwan, Tunyaluk
    Boonme, Prapaporn
    Khongkow, Pasarat
    Amnuaikit, Thanaporn
    BIOMED RESEARCH INTERNATIONAL, 2017, 2017
  • [9] New Perspectives on the Delivery of Nutrients and Bioactive Compounds through Gastric Restructuring of Foods
    Singh, Harjinder
    Acevedo-Fani, Alejandra
    JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY, 2022, 68 : S149 - S151
  • [10] PRONIOSOMES AND ETHOSOMES: NEW PROSPECT IN TRANSDERMAL AND DERMAL DRUG DELIVERY SYSTEM
    Pandey, Nidhi
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2011, 2 (08): : 1988 - 1996