A patient treated with ofatumumab for myasthenia gravis in conjunction with systemic lupus erythematosus and thyroid carcinoma

被引：0

作者：

Rong, Xi ^{[1
]}

Qu, Meijie ^{[1
]}

Jiang, Liwei ^{[2
]}

Liu, Min ^{[1
]}

机构：

[1] Qingdao Univ, Affiliated Hosp, Dept Neurol, 16 Jiangsu Rd, Qingdao 266000, Peoples R China

[2] Qingdao Univ, Affiliated Hosp, Dept Otolaryngol Head & Neck Surg, Qingdao, Peoples R China

来源：

INTRACTABLE & RARE DISEASES RESEARCH | 2024年 / 13卷 / 03期

关键词：

myasthenia gravis; ofatumumab; anti-CD20 monoclonal antibody;

D O I：

10.5582/irdr.2024.01022

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Myasthenia gravis (MG) is an autoimmune disease mediated by B cells and is associated with acetylcholine receptor (AChR) and muscle-specific receptor tyrosine kinase (MuSK) antibodies in the postsynaptic membrane at the neuromuscular junction. Anti-CD20 monoclonal antibodies, such as ofatumumab demonstrated promising disease control in MG patients. We presented the rare case of a 34-year-old female with acetylcholine receptor-positive myasthenia gravis (AChR-MG), concomitant with systemic lupus erythematosus (SLE) and metastatic thyroid carcinoma, who was treated with ofatumumab and exhibited improvements during follow-up.

引用

页码：195 / 198

页数：4

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