The Knowledge, Attitudes, and Practices Regarding Monkey Pox (Mpox) Among Undergraduate and Postgraduate Students in Gujarat, India

Background: The global spread of monkeypox (mpox) has raised concerns about public health preparedness, particularly among young adults. This study aimed to assess and compare the knowledge, attitudes, and practices (KAP) regarding mpox among undergraduate (UG) and postgraduate (PG) students in Gujarat, India. Methods: A cross-sectional study was conducted among 605 students (402 UG, 203 PG) from one of the tertiary hospitals (PG) and a medical colleges (UG) in Gujarat. A structured questionnaire assessed knowledge, attitudes, and practices regarding mpox. Data were analyzed using descriptive statistics, chisquare tests, and independent t-tests. Results: PG students demonstrated significantly higher knowledge scores than UG students (mean score 8.4 vs 6.5 out of 10, p<0.001). They showed greater awareness of mpox (187/203, 92.1% vs 314/402, 78.1%, p<0.001) and a better understanding of transmission routes, symptoms, and preventive measures. PG students also exhibited more positive attitudes, with a higher perception of mpox as a serious threat (152/203, 74.9% vs 241/402, 60.0%, p<0.001) and a greater willingness to get vaccinated (172/203, 84.7% vs 281/402, 69.9%, p<0.001). In terms of practices, PG students reported better adherence to preventive measures, including regular hand hygiene (127/203, 62.6% vs 201/402, 50.0% always practicing, p=0.002) and wearing face masks in crowded places (168/203, 82.8% vs 298/402, 74.1%, p=0.017). Conclusion: Significant differences in KAP regarding mpox exist between UG and PG students, with PG students consistently demonstrating higher levels of awareness, more positive attitudes, and better preventive practices. These findings highlight the need for targeted educational interventions to enhance mpox preparedness among university students, with particular attention to undergraduate populations.