Twins Early Development Study (TEDS): A genetically sensitive investigation of mental health outcomes in the mid-twenties

被引：20

作者：

Lockhart, Celestine ^{[1
]}

Bright, Joanna ^{[1
]}

Ahmadzadeh, Yasmin ^{[1
]}

Breen, Gerome ^{[1
,2
,3
]}

Bristow, Shannon ^{[1
]}

Boyd, Andy

Downs, Johnny ^{[4
,5
]}

Hotopf, Matthew ^{[5
,6
]}

Palaiologou, Elisavet ^{[1
]}

Rimfeld, Kaili ^{[1
,7
]}

Maxwell, Jessye ^{[1
]}

Malanchini, Margherita ^{[1
,8
]}

McAdams, Tom A. ^{[1
,9
]}

McMillan, Andrew ^{[1
]}

Plomin, Robert ^{[1
]}

Eley, Thalia C. ^{[1
,2
]}

机构：

[1] Kings Coll London, Inst Psychiat Psychol & Neurosci, Social Genet & Dev Psychiat Ctr, Room C1-16, London, England

[2] South London & Maudsley Hosp, UK Natl Inst Hlth Res NIHR Biomed Res Ctr, London, England

[3] Univ Bristol, Bristol Med Sch, Populat Hlth Sci, Bristol, England

[4] Kings Coll London, Dept Child & Adolescent Psychiat, Inst Psychiat Psychol & Neurosci, London, England

[5] South London & Maudsley NHS Fdn Trust, London, England

[6] Kings Coll London, Inst Psychiat Psychol & Neurosci, Dept Psychol Med, London, England

[7] Royal Holloway Univ London, Dept Psychol, Egham, Surrey, England

[8] Queen Mary Univ London, London, England

[9] Univ Oslo, Promenta Res Ctr, Oslo, Norway

来源：

JCPP ADVANCES | 2023年 / 3卷 / 02期

基金：

英国医学研究理事会;

关键词：

behavioural genetics; longitudinal studies; mental health; TEDS; twins; PSYCHOMETRIC PROPERTIES; BEHAVIOR PROBLEMS; VALIDATION; DEPRESSION; CHILDHOOD; SEVERITY; DISORDER; LIFE; QUESTIONNAIRE; MULTIVARIATE;

D O I：

10.1002/jcv2.12154

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

The Twins Early Development Study (TEDS) is a longitudinal study following a cohort of twins born 1994-1996 in England and Wales. Of the 13,759 families who originally consented to take part, over 10,000 families remain enrolled in the study. The current focus of TEDS is on mental health in the mid-twenties. Making use of over 25 years of genetically sensitive data, TEDS is uniquely placed to explore the longitudinal genetic and environmental influences on common mental health disorders in early adulthood. This paper outlines recent data collection efforts supporting this work, including a cohort-wide mental health assessment at age 26 and a multi-phase Covid-19 study. It will also provide an update on data linkage efforts and the Children of TEDS (CoTEDS) project.

引用

页数：11

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