Spatiotemporal whole-brain activity and functional connectivity of melodies recognition

被引：2

作者：

Bonetti, Leonardo ^{[1
,2
,3
,4
]}

Brattico, Elvira ^{[1
,2
,5
]}

Carlomagno, Francesco ^{[1
,2
]}

Cabral, Joana ^{[1
,2
,3
,6
]}

Stevner, Angus ^{[1
,2
,3
]}

Deco, Gustavo ^{[7
,8
]}

Whybrow, Peter C. ^{[9
]}

Pearce, Marcus ^{[1
,2
]}

Pantazis, Dimitrios ^{[10
]}

Vuust, Peter ^{[1
,2
]}

Kringelbach, Morten L. ^{[1
,2
,3
,4
]}

机构：

[1] Aarhus Univ, Ctr Mus Brain, Dept Clin Med, DK-8000 Aarhus Aalborg, Denmark

[2] Royal Acad Mus, DK-8000 Aarhus Aalborg, Denmark

[3] Univ Oxford, Linacre Coll, Ctr Eudaimonia & Human Flourishing, Oxford OX3 9BX, England

[4] Univ Oxford, Dept Psychiat, Oxford OX3 7JX, England

[5] Univ Bari Aldo Moro, Dept Educ, Psychol, Commun, I-70121 Bari, Italy

[6] Univ Minho, Life & Hlth Sci Res Inst ICVS, Sch Med, P-4710057 Braga, Portugal

[7] Univ Pompeu Fabra, Ctr Brain & Cognit, Computat & Theoret Neurosci Grp, Barcelona 08018, Spain

[8] Inst Catalana Recerca & Estudis Avancats ICREA, Passeig Lluis Co 23, Barcelona, Spain

[9] Univ Calif Los Angeles, Semel Inst Neurosci & Human Behav, Los Angeles, CA 90095 USA

[10] MIT, McGovern Inst Brain Res, Cambridge, MA 02139 USA

来源：

CEREBRAL CORTEX | 2024年 / 34卷 / 08期

基金：

新加坡国家研究基金会;

关键词：

memory; sequence recognition; brain spatiotemporal dynamics; functional connectivity; magnetoencephalography (MEG); CONTINGENT NEGATIVE-VARIATION; BASAL GANGLIA; MUSIC; MEG; MEMORY; CORTEX; MAGNETOENCEPHALOGRAPHY; INTELLIGENCE; PERCEPTION; SPACE;

D O I：

10.1093/cercor/bhae320

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Music is a non-verbal human language, built on logical, hierarchical structures, that offers excellent opportunities to explore how the brain processes complex spatiotemporal auditory sequences. Using the high temporal resolution of magnetoencephalography, we investigated the unfolding brain dynamics of 70 participants during the recognition of previously memorized musical sequences compared to novel sequences matched in terms of entropy and information content. Measures of both whole-brain activity and functional connectivity revealed a widespread brain network underlying the recognition of the memorized auditory sequences, which comprised primary auditory cortex, superior temporal gyrus, insula, frontal operculum, cingulate gyrus, orbitofrontal cortex, basal ganglia, thalamus, and hippocampus. Furthermore, while the auditory cortex responded mainly to the first tones of the sequences, the activity of higher-order brain areas such as the cingulate gyrus, frontal operculum, hippocampus, and orbitofrontal cortex largely increased over time during the recognition of the memorized versus novel musical sequences. In conclusion, using a wide range of analytical techniques spanning from decoding to functional connectivity and building on previous works, our study provided new insights into the spatiotemporal whole-brain mechanisms for conscious recognition of auditory sequences.

引用

页数：17

共 84 条

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