VITAMIN C: OVERVIEW OF DRUGS AND DIETARY SUPPLEMENTS AND ANALYTICAL METHODS FOR DETERMINING ITS CONTENT

被引:0
作者
Krukowski, Sylwester [1 ]
Bialy, Jakub [1 ]
Adamczyk, Aleksandra [1 ]
Kowalewska, Aleksandra [1 ]
机构
[1] Med Univ Warsaw, Fac Pharm, Chair & Dept Pharmaceut Chem & Biomat, Ul Banacha 1, PL-02097 Warsaw, Poland
来源
ACTA POLONIAE PHARMACEUTICA | 2024年 / 81卷 / 02期
关键词
vitamin C; ascorbic acid; ascorbate; drug; dietary supplement; determination; PERFORMANCE LIQUID-CHROMATOGRAPHY; L-ASCORBIC-ACID; SPECTROPHOTOMETRIC DETERMINATION; FLUOROMETRIC-DETERMINATION; DEHYDROASCORBIC ACID; ELECTROCHEMICAL DETERMINATION; PHARMACEUTICAL-PREPARATIONS; QUANTIFICATION; STABILITY; ELECTRODE;
D O I
10.32383/appdr/187234
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Vitamin C is one of the most well-known and most frequently used substances found in various pharmaceutical preparations. Patients consider it a safe compound with multidirectional beneficial effects, while chemists have been presenting various possibilities for its determination for many years. The aim of this review is to present the current range of drugs and dietary supplements containing vitamin C available in Poland, divided into appropriate categories, taking into account doses, forms, and other ingredients. The second goal is to summarize the main analytical methods for determining the content of ascorbic acid. A review of the available preparations showed disproportions between a small group of drugs and a very large group of dietary supplements, which turned out to be significantly diversified in various aspects. In turn, the review of analytical methods clearly indicates the dominant share of spectroscopic ones and the fact that researchers focus primarily on improving basic, commonly known techniques.
引用
收藏
页码:239 / 262
页数:24
相关论文
共 115 条
  • [91] A spectrophotometric determination of ascorbic acid
    Shrivas, K
    Agrawal, K
    Patel, DK
    [J]. JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 2005, 52 (03) : 503 - 506
  • [92] Skrovankova S, 2015, INT J ELECTROCHEM SC, V10, P2421
  • [93] Determination of vitamin C in foods: Current state of method validation
    Spinola, Vitor
    Llorent-Martinez, Eulogio J.
    Castilho, Paula C.
    [J]. JOURNAL OF CHROMATOGRAPHY A, 2014, 1369 : 2 - 17
  • [94] USE OF 2,6-DICHLOROPHENOL-INDOPHENOL AS INDICATOR IN IODOMETRIC TITRATIONS WITH ASCORBIC ACID
    SVEHLA, G
    KOLTAI, L
    ERDEY, L
    [J]. ANALYTICA CHIMICA ACTA, 1963, 29 (05) : 442 - &
  • [95] Spectrophotometric Determination of L-Ascorbic Acid in Pharmaceuticals
    Szpikowska-Sroka, B.
    Poledniok, J.
    [J]. JOURNAL OF ANALYTICAL CHEMISTRY, 2011, 66 (10) : 941 - 945
  • [96] Determination of ascorbic acid and its degradation products by high-performance liquid chromatography-triple quadrupole mass spectrometry
    Szultka, Malgorzata
    Buszewska-Forajta, Magdalena
    Kaliszan, Roman
    Buszewski, Boguslaw
    [J]. ELECTROPHORESIS, 2014, 35 (04) : 585 - 592
  • [97] Dual-emission biomass carbon dots for near-infrared ratiometric fluorescence determination and imaging of ascorbic acid
    Tang, Cui
    Long, Ruiqing
    Tong, Xia
    Guo, Ying
    Tong, Chaoying
    Shi, Shuyun
    [J]. MICROCHEMICAL JOURNAL, 2021, 164
  • [98] Direct amperometric determination of L-ascorbic acid (Vitamin C) at octacyanomolybdate-doped-poly(4-vinylpyridine) modified electrode in fruit juice and pharmaceuticals
    Thangamuthu, R.
    Kumar, S. M. Senthil
    Pillai, K. Chandrasekara
    [J]. SENSORS AND ACTUATORS B-CHEMICAL, 2007, 120 (02): : 745 - 753
  • [99] Redox Interactions of Vitamin C and Iron: Inhibition of the Pro-Oxidant Activity by Deferiprone
    Timoshnikov, Viktor A.
    Kobzeva, Tatyana, V
    Polyakov, Nikolay E.
    Kontoghiorghes, George J.
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (11)
  • [100] Quantification of ascorbic acid and sodium ascorbate in powder blends for tableting and in vitamin C chewable tablets by NIR-chemometry
    Tomuta, Ioan
    Dudas, Dana
    Vonica, Andreea Loredana
    Leucuta, Sorin E.
    [J]. ACTA PHARMACEUTICA, 2013, 63 (03) : 373 - 384